Our knowledge of the pathophysiology about traumatic brain injury (TBI) is still limited. Neutrophils, as the most abundant leukocytes in circulation and the first-line transmigrated immune cells at the sites of injury, are highly involved in the initiat
resulting in poor goal-directed behavior [3,5–8] and significant decreases in independent functioning in both soldiers and returning veterans. Given the necessity for operational effectiveness in the battlefield environment, executive
We hypothesized that progesterone reduces peri-contusional recruitment of leukocytes to a greater extent than either osmotherapy a day after TBI. Methods CD1 mice underwent controlled cortical impact (CCI) and were treated with osmotherapy (mannitol & hypertonic saline)......
Anatomical data (T1-weighted multi-echo magnetization prepared—rapid gradient echo sequence—MEMPRAGE—1 mm isotropic resolution) was acquired with the full 3d channel coil after the functional imaging. In addition, we acquired a set of whole-head EPIs in both head-foot and foot-head encoding ...