英文名称: TAS2R14 agonist-2 总访问: 55 国产/进口: 进口 半年访问: 11 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg 最后更新: 2025-2-13 货号: HY-153265 CAS 号: 2883007-69-8 参考报价: 2695; 2450; 3900; 8200 立即询价 电话咨询 ...
MCE 站:TAS2R14 agonist-2 产品活性:TAS2R14 agonist-2 (compound 28.1) 是一种有效的选择性 TAS2R14 抑制剂,EC50 值为72 nM。 研究领域:Others 作用靶点:Others 相关产品:Antitumor agent-67 | Catechin 7-O-β-D-glucopyranoside | Carbobenzoxyproline | ATR-IN-9 | TBTDC | Peucenin 7-O-methy...
et al. Comparing class A GPCRs to bitter taste receptors: structural motifs, ligand interactions and agonist-to-antagonist ratios. Methods Cell. Biol. 132, 401–427 (2016). Article PubMed Google Scholar Hanson, M. A. et al. A specific cholesterol binding site is established by the 2.8 ...
Bitter taste receptor-14 (TAS2R14) is a GPCR also expressed on human airway smooth muscle cells, which signals to intracellular [Ca ], resulting in relaxation of the airway, and is a novel target for bronchodilators. Here, we examine long-term, agonist-promoted down-regulation of TAS2R14...
et al. Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist. Cell Res 34, 735–738 (2024). https://doi.org/10.1038/s41422-024-00995-4 Download citation Received06 May 2024 Accepted23 June 2024 Published05 July 2024 Issue DateOctober 2024 DOIhttps://...
Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist 目的:探讨射干麻黄汤辛,苦味药组对哮喘寒哮证大鼠肺组织中瞬时受体电位通道香草醛亚型1(TRPV1),苦味受体14(TAS2R14)蛋白表达的影响.方法:70只SD大鼠随机分为正常组,模... L Tao,D Wang,Q Yuan,... - 《Cell...
查看相关系列 TAS2R14 Agonist (20) 所有研究领域 Skip to the end of the images gallery Skip to the beginning of the images gallery 基本描述 别名 三丁酸甘油酯 英文别名 propane-1,2,3-triyl tributanoate | Tox21_303991 | Butyric acid triester with glycerin | Tributin | BRN 1714746 | ...
查看相关系列 TAS2R14 Agonist (20) TAS2R39 Agonist (12) 所有研究领域 Skip to the end of the images gallery Skip to the beginning of the images gallery 基本描述 别名 达提素 英文别名 LMPK12111622 | C.I. 75630 | 3,5,7,2'-Tetrahydroxyflavone | 4H-1-Benzopyran-4-one, 3,5,7-...
Highly conserved intracellular H208 residue influences agonist selectivity in bitter taste receptor T2R14 Biochimica et Biophysica Acta (BBA) - Biomembranes, 1861 (12) (2019), Article 183057, 10.1016/j.bbamem.2019.183057 View PDFView articleView in ScopusGoogle Scholar Slack et al., 2010 J.P. ...
Conclusions: FFA as a potent TAS2R14 agonist to relax ASMCs while suppressing cytokine release might be a favorite drug agent for further development of TAS2R-based novel dual functional medication for bronchodilation and anti-inflammation in asthma therapy....