英文名称: TAS2R14 agonist-2 总访问: 55 国产/进口: 进口 半年访问: 11 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg 最后更新: 2025-2-13 货号: HY-153265 CAS 号: 2883007-69-8 参考报价: 2695; 2450; 3900; 8200 立即询价 电话咨询 ...
MCE 站:TAS2R14 agonist-2 产品活性:TAS2R14 agonist-2 (compound 28.1) 是一种有效的选择性 TAS2R14 抑制剂,EC50 值为72 nM。 研究领域:Others 作用靶点:Others 相关产品:Antitumor agent-67 | Catechin 7-O-β-D-glucopyranoside | Carbobenzoxyproline | ATR-IN-9 | TBTDC | Peucenin 7-O-methy...
Bitter taste receptor-14 (TAS2R14) is a GPCR also expressed on human airway smooth muscle cells, which signals to intracellular [Ca ], resulting in relaxation of the airway, and is a novel target for bronchodilators. Here, we examine long-term, agonist-promoted down-regulation of TAS2R14...
Strychnine is an agonist for TAS2R46. The conformational changes are indicated by red arrows. (f) The sequence alignment of conserved residues in TAS2Rs (TAS2R14 and TAS2R46) and class A GPCRs (β2AR and CB1). (g) The 3D structural comparison of TAS2R14 with TAS2R46 and β2AR...
et al. Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist. Cell Res 34, 735–738 (2024). https://doi.org/10.1038/s41422-024-00995-4 Download citation Received06 May 2024 Accepted23 June 2024 Published05 July 2024 Issue DateOctober 2024 DOIhttps://...
Highly conserved intracellular H208 residue influences agonist selectivity in bitter taste receptor T2R14 Biochimica et Biophysica Acta (BBA) - Biomembranes, 1861 (12) (2019), Article 183057, 10.1016/j.bbamem.2019.183057 View PDFView articleView in ScopusGoogle Scholar Slack et al., 2010 J.P. ...
Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist 目的:探讨射干麻黄汤辛,苦味药组对哮喘寒哮证大鼠肺组织中瞬时受体电位通道香草醛亚型1(TRPV1),苦味受体14(TAS2R14)蛋白表达的影响.方法:70只SD大鼠随机分为正常组,模... L Tao,D Wang,Q Yuan,... - 《Cell...
查看相关系列 TAS2R14 Agonist (20) 所有研究领域 Skip to the end of the images gallery Skip to the beginning of the images gallery 基本描述 别名 三丁酸甘油酯 英文别名 propane-1,2,3-triyl tributanoate | Tox21_303991 | Butyric acid triester with glycerin | Tributin | BRN 1714746 | ...
查看相关系列 TAS2R14 Agonist (20) TAS2R39 Agonist (12) 所有研究领域 Skip to the end of the images gallery Skip to the beginning of the images gallery 基本描述 别名 达提素 英文别名 LMPK12111622 | C.I. 75630 | 3,5,7,2'-Tetrahydroxyflavone | 4H-1-Benzopyran-4-one, 3,5,7-...
Conclusions: FFA as a potent TAS2R14 agonist to relax ASMCs while suppressing cytokine release might be a favorite drug agent for further development of TAS2R-based novel dual functional medication for bronchodilation and anti-inflammation in asthma therapy....