It is likely that adipose tissue, particularly in the intra-abdominal depot, is part of a complex interplay involving several tissues and that dysregulated hormonal, metabolic and neural signalling within and between organs can trigger development of metabolic disease. One attractive hypothesis is that...
(Montagne et al., 1999). In mice lacking S6K1, body size was significantly smallerversusthe wild type at birth and during postnatal growth, attributing by the reduced size in all organs (Shima et al., 1998). The reduction in size of organs was probably caused by decreased cell siz...
b.Any of various organs, such as lymph nodes, that resemble true glands but perform a nonsecretory function. 2.BotanyAn organ or a structure that secretes a substance. [Frenchglande, from Old Frenchglandre, alteration of Latinglandula, diminutive ofglāns, gland-,acorn.] ...
Insulin-dependent diabetes mellitus (IDDM) develops spontaneously by 80 - 120 days of age in approximately 50% of animals from high-risk lines of Wistar BioBreeding (BB) rats. In addition, these rats also show subclinical evidence of autoimmunity against several endocrine and lymphoid organs.IDDM...
b, c Relative mRNA values of Ahsg (b) or Apoc2 (c) in E18.5 kidneys (circles) or liver samples (squares) shown as mean ± SEM. N = fetal organs. Kidney and liver samples are analyzed separately. Note the logarithmic scale on the y-axis. d, e Serum fetuin-A levels ...
The company can also make various zebrafish organs visible by tagging the tissues with fluorescent markers. One of the most widely used models of human disease is the mouse, but working with mice can be both time-consuming and expensive. Lexicon Genetics has met this challenge by industrializing...
Raev DC (1994) Left ventricular function and specific diabetic complications in other target organs in young insulin-dependent diabetics: an echocardiographic study. Heart Vessels 9: 121-128.Raev DC (1994) Left ventricular function and specific diabetic complications in other target organs in young ...
Comparative aspects of the growth promoting actions of prolactin on its target organs: evidence for synergism with an insulin-like growth factor 来自 ResearchGate 喜欢 0 阅读量: 17 作者:C Nicoll,T Anderson,N Hebert,S Russell 被引量: 7
Professor de Magalhaes highlights the important role that cellular senescence plays in the development of several tissues and organs as well as: inflammation andwound healing, tumor suppression, insulin secretioninpancreatic beta cells, and has structural roles in the vascular system and placenta. ...
Our personal approach is to review target organs in all dose groups, whether there was a treatment-related change or not. In some cases, where the target organ has a number of changes in addition to the treatment-related change, we may opt to review all of the target organs in all dose...