T cellsBONE marrowDISEASE relapseCYTOPENIALEUKEMIAdoi:10.1093/qjmed/hcae086Murphy PhilipQJM: An International Journal of Medicine
T淋巴母细胞性白血病/淋巴瘤,非特指 T-lymphoblastic leukaemia / lymphoma, NOS 早期前驱T细胞性白血病/淋巴瘤Early T-precursor lymphoblastic leukaemia / lymphoma 成熟T和NK细胞肿瘤Mature T- and NK-Cell Neoplasms 成熟T和NK细胞白血病 Mature T- and NK-Cell Neukemia ...
Large granular lymphocytic leukaemia (LGL-T) is associated with a permanent increase in granular lymphocytes (CD3+) in the peripheral blood. Frequently it is associated with neutropenia and auto-immune diseases. However, these cases are to be distinguished from the NK-leukaemia (characterised by a...
AIM: To define the relation between T large granular lymphocyte (T-LGL) leukaemia and pure red cell aplasia in Chinese patients. METHODS: Patients with T-LGL leukaemia were identified from a consecutive series of Chinese patients with chronic lymphoproliferative disorders. The diagnosis of T-LGL ...
Table 4 Amino-acid sequences of CDR3 motifs of in-frame TCRA rearranged alleles in patients with CD8+/TCRαβ+T-LGL leukaemia Full size table When visualizing the TCRA and TCRB combinatorial diversity using the Circoletto tool, both the Vα-Jα and Vβ-Jβ diversities were indeed largely...
T-LGL cells arise as a consequence of chronic antigenic stimulation and inflammation and thrive because of constitutive activation of the STAT3 and ERK pathway. Notably, in 40% of patients, constitutive STAT3 activation is due to STAT3 activating mutatio
Summary The effect of pregnancy on T-cell large granular lymphocyte (LGL) leukaemia has not been previously described. We retrospectively reviewed the clinical features of three patients with T-cell LGL leukaemia; each of them had one or more pregnancies during disease evolution. Pregnancy was assoc...
Leukaemia,CLL)、急性淋巴细胞白血病 (Acute Lymphoblastic Leukaemia,ALL)、套细胞白血病、毛细胞白血病、胰腺癌、前列腺 癌、结肠癌、膀胱癌、卵巢癌、恶性胶质瘤、睾丸癌、子宫癌、肾上腺癌、乳腺癌、肺癌、黑素瘤、 神经母细胞瘤、肉瘤、肾癌。此外,ROR1在癌症干细胞的子集上表达。 [0003]最近,已经对T细胞进行了...
Benign clonal T-cell expansions in reactive immune responses often complicate the laboratory diagnosis T-cell neoplasia. We recently introduced a novel flow cytometry assay to detect T-cell clones in blood and bone marrow, based on the identification of a monophasic T-cell receptor (TCR) β chain...
AimsT cell large granular lymphocytes (T-LGLs) are commonly increased in reactive conditions as well as T-LGL leukaemia. This differential diagnosis often ... B Feng,JL Jorgensen,Y Hu,... - 《Journal of Clinical Pathology》 被引量: 46发表: 2010年 加载更多研究点推荐 phocyte singlecell RNA...