Resting memory CD4 T cellsHIV reservoirViral controlThe HIV reservoir is the main barrier to eradicating HIV infection, and resting memory CD4 T (Trm) cells are one of the most relevant cellular component harboring latent proviruses. This is the first study analyzing the transcriptional profile of...
Unlike memory CD8 T cells and plasma cells, which reside in bone marrow niches, it had been presumed that memory CD4 T cells constantly circulate in the body for surveillance. Now, Tokoyoda and colleagues show that memory CD4 T cells do in fact reside and rest in the bone marrow, where ...
名称:EasySep™ 人静息CD4+T细胞分选试剂盒 品牌:STEMCELL 产品描述:Immunomagnetic negative selection kit 购买数量: 立即购买 产品信息 The EasySep™ Human Resting CD4+ T Cell Isolation Kit is designed to isolate resting CD4+ T cells from fresh or previously frozen human peripheral blood mononuclear ...
Taken together, we conclude that CD4+ T cells mediate obesity memory and promote weight regain. Cellular & Molecular Immunology advance online publication, 19 June 2017; doi:10.1038/cmi.2017.36 Keywords: CD4+ T cell; immunodeficiency; metabolism; obesity memory; weight regain INTRODUCTION Obesity is...
resting CD4 T cells HIV-1 nuclear import Vpx Research topic(s) CP: Immunology CP: Microbiology Introduction CD4 T cells are the major targets of HIV-1 in vivo, and their permissivity to productive infection is dictated by their activation state. The CD4 T cell repertoire residing within lymph...
Latent HIV-1 infection of resting memory CD4(+) T cells represents the major barrier to HIV-1 eradication. To determine whether the CCR7 ligands involved i... S Saleh,A Solomon,F Wightman,... - 《Blood》 被引量: 157发表: 2008年 Restrictions to HIV-1 replication in resting CD4+ T lym...
In agreement with recent studies, the optimal generation of functional memory CD8 T cells required CD4 help, although long-term maintenance of resting CD8 memory T cells did not absolutely depend on the presence of CD4 T cells. Nonetheless, CD4 T cells were essential during differentiation of ...
Once infection is cleared, memory Th cells are generated over time following the death of the majority of effector cells. These memory cells can quickly respond to a secondary infection in an antigen-specific manner. Some studies have suggested that CD4+ memory cells are found in the bone ...
Alpha4(+)beta7(hi)CD4(+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection. Human immunodeficiency virus/simian immunodeficiency virus (HIV/SIV) infections are believed to infect minimally activated CD4(+) T cells after viral entry... M Kader,X...
2 reagents referenced in Latent HIV-1 infection of resting CD4⁺ T cells in the humanized Rag2⁻/⁻ γc⁻/⁻ mouse.