Journal of the International AIDS Society 2010, 13(Suppl 3):O2 http://www.jiasociety.org/content/13/S3/O2 ORAL PRESENTATION Open Access Most HIV DNA in PBMC is present in non-gut homing, resting memory CD4+ T c
Available online http://arthritis-research.com/content/10/2/R36 ResearchVol10No2 article Open Access Resting CD4+ effector memory T cells are precursors of bystander-activated effectors: a surrogate model of rheumatoid arthritis synovial T-cell function Fionula M Brennan1, Nicola MG Smith1, Sally...
Long-lived resting memory CD4+ T cells (TCM) are a major reservoir of latent HIV infection. We hypothesized that latent HIV-TCM cells are maintained by aberrant expression of cell survival factors, including XIAP, BIRC2/cIAP1, and beclin-1. DIABLO/SMAC mimetics are therapeutic agents that com...
Subsequently, we determined the expression of KRT72 in various host cells. KRT72 is highly expressed in resting CD4+T cells (Fig.1b, c), expressed to some extent in hair follicle stem cells (Supplementary Fig.1b) but not stimulated CD4+T lymphocytes, primary macrophages, dendritic cells, 2...
Cutting edge: L-selectin (CD62L) expression distinguishes small resting memory CD4+ T cells that preferentially respond to recall antigen. Cutting edge: L- selectin (CD62L) expression distinguishes small resting memory CD4+ T cells that preferentially respond to recall antigen. J Immunol. ... ...
Latent HIV-1 persists in resting memory CD4+ T cells, even in patients receiving highly active antiretroviral therapy (HAART). It has been unclear how stable this latent reservoir is and whether its persistence reflects replenishment by low-level viremia
货号: 17962;17962RF 名称: EasySep™ 人静息CD4+T细胞分选试剂盒 品牌: STEMCELL 产品描述: Immunomagnetic negative selection kit 购买数量: 立即购买 产品信息 The EasySep™ Human Resting CD4+ T Cell Isolation Kit is designed to isolate resting CD4+ T cells from fresh or previously frozen...
cells and tissue reservoirs (e.g., lymph node, spleen, bone marrow) following HIV-1 infection with the CCR5-tropic JR-CSF strain and suppression of viremia by ART. Replication-competent virus was recovered from pooled resting CD4⁺ T cells in 7 of 16 mice, with a median frequency of ...
By combining cell purification and enzyme-linked immunospot assay, we found that effector CD27− T cells, which promptly produced cytokines in response to antigen (Ag), and memory-resting CD27+ T cells, which required Ag restimulation to perform their functions, were maintained in both XLA ...
Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4⁺ T cells to T-regulatory cells.Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4⁺ T cells to T-regulatory cells. P...