T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to sense and respond to diverse types of infection. ...
Stockinger B, Veldhoen M, Martin B (2007) Th17 T cells: linking innate and adaptive immunity. Semin Immunol 19(6):353–361. : 10.1016/j.smim.2007.10.008Stockinger et al., " Th17 T cells: linking innate and adaptive immunity "; Semin. Immunol.; vol. 19; No...
B B T T T T T 刀豆蛋白A T T T T T T淋巴细胞概念、性质和作用 Cells of Adaptive immunity ---T lymphocytes 学习要点 1.掌握阴性选择和阳性选择的概念及作用。 2.掌握T细胞主要表面分子及其作用。 3.掌握T细胞亚群分类方法及各亚群特性。 4.掌握T细胞的功能。 5.熟悉调节性T细胞的功能。 T 淋巴细胞...
It is thus possible to re-explain the 'self' / 'non-self' concept based on 'homotype (phase)' / 'heterotype (phase)' recognition at the level of a single clone of T cells. Hence adaptive immunity is explained here as being derived from functions that ensure synchronous ontogeny and ...
T cells are the central mediators of both humoral and cellular adaptive immune responses. Highly specific receptor-mediated clonal selection and expansion of T cells assure antigen-specific immunity. In addition, encounters with cognate antigens generate
Liu M, Li S, Li MO. TGF-β control of adaptive immune tolerance: a break from Treg cells. Bioessays. 2018;40(11):e1800063. doi:10.1002/bies.201800063 Lu L, Barbi J, Pan F. The regulation of immune tolerance by FOXP3. Nat Rev Immunol. 2017;17(11):703-717. doi:10.1038/nri...
Role of T Cells T cells are primarily involved in adaptive rather than innate immune responses. Adaptive immunity is mediated by both CD4 and CD8-positive T cells and by antibody-producing B cells. Adapt...
免疫细胞可以大致分为先天性免疫细胞(innate immune cells),以及适应性免疫细胞(adaptive immune cells)两类,它们可以分别启动针对抗原的非特异性和特异性免疫反应。适应性免疫细胞主要有两大类,B细胞主要靠分泌特异性抗体实现对抗原的细胞...
CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation[J]. Cancer Cell, 2010, 18(5): 485-498. DOI: 10.1016/j.ccr.2010.10.002. [11]Schn...
这种方法在1984年开始用于临床探索性研究中,当时这种技术手段被命名为淋巴因子激活的杀伤细胞(lymphokine-activated killer cells,LAK)疗法[2]。随后,又有细胞因子诱导的杀伤细胞(cytokineinduced killer,CIK)方法以及加强型的树突状细胞和淋巴细胞混合培养和回输(DC-CIK)问世[3],进而有肿瘤浸润淋巴细胞(tumor ...