[1]Ganapathy T,et al.CAR γδ T cells for cancer immunotherapy. Is the field more yellow than green? Cancer Immunol Immunother. 2023 Feb;72(2):277-286. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10992831/ ...
利用T细胞递送溶瘤病毒 浙江大学药学院/良渚实验室平渊团队在Nature Biotechnology期刊发表了题为“An oncolytic virus–T cell chimera for cancer immunotherapy”的研究论文,报道了一种ONCOTECH的技术(溶瘤病毒-T细胞嵌合体)。 ONCOTECH技术的核心在于构建了一种表达CRISPR/Cas9的溶瘤腺病毒,并通过特定抗原表达的生物...
7. June CH, O’Connor RS, Kawalekar OU, Ghassemi S, Milone MCCAR. T cell immunotherapy for human cancer. Science. 2018;359:1361–1365. doi: 10.1126/science.aar6711. - DOI - PubMed 8. Sadelain M, Brentjens R, Rivière I. The basic principles of chimeric antigen receptor design. Ca...
Sewell. Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 2023: 186(16), P3333-3349.E27. DOI: doi.org/10.1016/j.cell. 多快好省,购物逛京东!m.jd.com/#sksLeft=0&st=0&fls08007=undefined...
Immunotherapy based on the adoptive transfer of naturally occurring or gene-engineered T cells can mediate tumour regression in patients with metastatic cancer. Here, we discuss progress in the use of adoptively transferred T cells, focusing on how they can mediate tumour cell eradication. Recent ad...
Cancer immunotherapy aims to promote the activity of cytotoxic T lymphocytes (CTLs) within a tumour, assist the priming of tumour-specific CTLs in lymphoid organs and establish efficient and durable antitumour immunity. During priming, help signals are relayed from CD4+ T cells to CD8+ T cells...
New immune cell engagers for cancer immunotherapy. Nat Rev Immunol. 2024 Jan 25. doi: 10.1038/s41577-023-00982-7IF: 100.3 Q1 . Epub ahead of print. PMID: 38273127IF: 100.3 Q1 .编辑于 2024-04-27 13:33・IP 属地上海 癌症治疗 癌症生物学 癌症...
这篇论文的题目是《PHGDH 介导的内皮代谢驱动胶质母细胞瘤对嵌合抗原受体 T 细胞免疫治疗的抵抗》（PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor Tcell immunotherapy），张铎是第一作者，樊懿担任通讯作者。图 | 相关论文（来源：Cell Metabolism）这是一项宏大的研究...
纳米抗体联合CAR-T，改变癌症治疗的未来 导读嵌合抗原受体T细胞（Chimeric Antigen Receptor T-cell，CAR-T）疗法是一种新兴的细胞免疫治疗，通过基因工程改造T细胞，使其在细胞表面表达嵌合抗原受体（Chimeric Antigen Receptor T-cell，CAR）。这种受体赋予T细胞识别特定靶细胞表面抗原的能力，并能够对这些表达抗原的细胞...
T-cell immunotherapy of cancer In animal systems, complete and permanent eradication of tumours can be achieved by adoptive transfer of MHC-restricted T cells, combined with IL2. In cert... CJM Melief,WM Kast - 《Research in Immunology》 被引量: 78发表: 1991年 CAR T-cells for cancer ther...