T-cell-based immunotherapies hold promise for the treatment of many types of cancer, with three approved products for B-cell malignancies and a large pipeline of treatments in clinical trials. However, there are several challenges to their broad implemen
T-cell-based immunotherapies hold promise for the treatment of many types of cancer, with three approved products for B-cell malignancies and a large pipeline of treatments in clinical trials. However, there are several challenges to their broad implemen
nanomedicine targeting CAFs holds significant promise for advancing cancer immunotherapy (Wang et al.2023a). By leveraging the unique properties of nanomaterials
Factors leading to the immune escape may be failure to detect tumor antigens, Tregs expansion from DC priming, or suppression of T-cell function in tumors by factors in the TME [20]. Cancer immunotherapy aims to initiate or re-implement the cancer-immunity cycle (Fig. 1). For example, ...
Nanomaterials for T-cell cancer immunotherapy This Review discusses the progress and the remaining challenges for the clinical application of nanomaterial-based T-cell immunotherapies. Ningqiang Gong Neil C. Sheppard Michael J. Mitchell Review Article12 Jan 2021 Nature Nanotechnology Image...
Cancer immunotherapy has been intensively investigated in both preclinical and clinical studies. Whereas chemotherapies use cytotoxic drugs to kill tumor cells, cancer immunotherapy is based on the ability of the immune system to fight cancer. Tumors are i...
Immunotherapy has developed rapidly in recent years and has become a research hotspot. Currently, chimeric antigen receptor T-cell immunotherapy and immune checkpoint inhibitors are the most effective tumor immunotherapies in clinical practice. While tumor immunotherapy brings hope to patients, it also ...
(SDT) are being used in cancer treatment. In addition, a substantial number of studies on variety of therapies such as molecular therapy, apoptosis regulations, immunotherapy, signal modification therapy, nucleic-acid-based therapy, and anti-angiogenesis therapy for the treatment of cancer have been...
Cancer immunotherapyDrug deliveryNanoparticlesProf. Bourquin and her group focus on novel bioinspired strategies for the targeting of the immune system to treat cancer. The group investigates how nanoparticles of different types can be used to mimic bacteria or viruses in order to trigger immunity in ...
Role of Nanomedicine for Cancer Immunotherapy Introduction Malignant tumors are one of the most life-threatening diseases around the world [1,2]. Although molecular typing and the emergence of comprehensive treatment plans have greatly improved the survival outcomes of patients [3], local recurrence an...