T cell cytokine production in childhood asthma. Curr Resp Med Rev 2005; 1: 1-6.V. G. Brown and M. Ennis, "T cell cytokine production in childhood asthma," Current Respiratory Medicine Reviews, vol. 1, pp. 1-16, 2005.Brown, V.G.; Ennis, M. T cell cytokine production in childhood...
Cytokine production by synovial T cells in rheumatoid arthritis. Rheumatology (Oxford). 1999;38(3):202-13.Steiner G, Tohidast-Akrad M, Witzmann G, Vesely M, Studnicka- Benke A, Gal A, et al. Cytokine production by synovial T cells in rheumatoid arthritis. Rheumatology (Oxford). 1999;...
Th1 and Th2 cells, which differed from each other in their pattern of cytokine production and their functions.
T cell–derived cytokines are important in the development of an effective immune response, but when dysregulated they can promote disease. Here we identify a four-helix bundle cytokine we have called interleukin 31 (IL-31), which is preferentially produ
Cytokine Beads Array (CBA) assay. For most cytokines, with the exception of those highlighted in red (IP-10, MIG, MDC), acidic conditions evoked a reduction in release.fRate of B6 cell proliferation measured by CellTrace Violet assay.gIFNγ production was measured, by ELISA, at the end ...
176 Similarly, Tregs were found to promote the stemness of acute myeloid leukemia (AML) via releasing anti-inflammatory cytokine IL-10 and subsequently activating the PI3K/AKT signal pathway.177 Further transgenic mice mode validated that blocking the interaction between Tregs and AML cells might be...
Little is known about the type 1/type 2 T cell dichotomy in old age. Peripheral blood mononuclear cells (PBMC) and T cell lines from old and young healthy individuals were therefore analyzed for their production of interferon gamma (IFN-γ) and interleukin 4 (IL-4). Tetanus toxoid (TT),...
外周血中大约90% NK细胞为 CD16+CD56dim亚群,表面表达杀伤细胞免疫球蛋白样受体(killer-cell immunoglobulin-like receptor,KIR)和CD57,这群细胞通过产生穿孔素、颗粒酶和抗体依赖细胞介导的细胞毒性作用(antibody dependent cellular cytotoxicity,ADCC)发挥细胞毒作用;而占约10%...
7B). As expected, IFI35-induced CD8+ T cell proliferation (Fig. 7C, D) and cytokine secretion (Fig. 7E–H) were completely blocked by the inhibitor of PI3K, which suggests that PI3K/AKT/mTOR signaling pathway is required for IFI35-mediated activation of CD8+ T cells. Taken together, ...
This could be due to reduced proliferation of T cells, evident at biochemical level by defects in proximal TCR signaling cascade activation [3–5] and calcium signaling [6], and at cellular level by defects in cytokine production [7] and differentiation to Th1 or Th2 effector cells [8]. ...