1. Hori, S., Nomura, T. & Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3.Science299, 1057–1061 (2003). 2. Zappasodi, R. et al. Non-conventional inhibitory CD4+Foxp3−PD-1hi T cell...
T 细胞按照功能和表面标志可以分为:细胞毒性 T 细胞(cytotoxic T cell,主要表面标志是 CD8),辅助 T 细胞(helper T cell,主要表面标志是 CD4),调节/抑制 T 细胞(regulatory/suppressor T cell,目前研究最活跃的是 CD25 CD4 T 细胞),以及记忆 T 细胞 (memory T...
(1995) Regulation of CD4 T cell reactivity to self and non-self. Int. Rev. Immunol. 13 , 147–160.Lo D, Reilly C, Marconi LA, et al. Regulation of CD4 T cell reactivity to self and non-self. Int Rev Immunol 1995;13:147-160....
T 细胞按照功能和表面标志可以分为:细胞毒性 T 细胞(cytotoxic T cell,主要表面标志是 CD8),辅助 T 细胞(helper T cell,主要表面标志是 CD4),调节/抑制 T 细胞(regulatory/suppressor T cell,目前研究最活跃的是 CD25 CD4 T 细胞),以及记忆 T 细胞 (memory T cell,暂时没有非常特异的表面标志)。 涉及到免...
While much is known in CD8+ (killer) T cells [6], the expansion of CD4+ (helper) T cells during an infection is less well understood at the cellular and molecular levels. How does the coupling between differentiation and the cell cycle occur in CD4+ T cells? Are the two processes ...
Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol Cell Biol 1998; 76: 34–40. Article CAS PubMed Google Scholar Sharpley CF, Agnew LL . Cytokines and depression: findings, issues, ...
CD4+ T cell counts in peripheral blood,patients were divided into Group A(CD4200/μL),Group B(CD4 200～400/μL) and Group C(CD4400/μL),respectively.The CD4+CD25+Foxp3+ regulatory T cells were examined with intracellular staining flow cytometric technique.The relationship between CD4+ T ...
Regulatory T Cell In subject area: Immunology and Microbiology Tregs (regulatory T cells) are one among the subsets of CD4+ T cells that express the IL-2 receptor α chain (CD25) and help to sustain homeostasis and self-tolerance by controlling immune responses....
RegulatoryTcells(regulatory,t,cell,TR)canblocktheinflammatoryresponsetoautoantigensandlimitthedevelopmentofautoimmunediseases.Theseimmuneregulatorycellsexistintwoways:oneisnaturallyoccurringcellsinthebody,andtheotheristhecellsthatareinducedbytheinduction.Thisreviewfocusesonthemolecularmarkersandmechanismsofactionofcd4+...
Regulatory Status: RUO RRID: AB_2869213 Description The BD IMag™ Human Naïve CD4+ T Cell Enrichment Set - DM is used for the negative selection of untouched naïve CD4+ T cells from peripheral blood. The Human Naïve CD4+ T Cell Enrichment Cocktail ...