T cell activation and the cytoskeleton. Annu Rev Immunol 2000; 18:165-84.Acuto, O., and D. Cantrell. 2000. T cell activation and the cytoskeleton. Annu. Rev. Immunol. 18:165.Acuto O,,Cantrell D.T cell activation and the cytoskeleton. Annual Review of Immunology . 2000...
The T-cell cytoskeleton is a complex intracellular network of structural, adaptor and signalling molecules. This Review discusses recent advances in our understanding of its role in the initiation and maintenance of T-cell activation during antigen-prese
Role of EGF-induced tyrosine phosphorylation of reggie-1/flotillin-2 in cell spreading and signaling to the actin cytoskeleton. Cholesterol and sphingolipid-rich membrane microdomains or rafts have been shown to be involved in signaling through many growth factor receptors but the m... Neumann-Giesen...
Volume 107, Issue Supplement s1, pages 29–30, December 2002 Additional Information How to Cite (2002), Dynamics of T-cell activation: shape change and the actin cytoskeleton (Biochemical Immunology Group). Immunology, 107: 29–30. doi: 10.1046/j.1365-2567.107.s1.58.x Publication History Issue...
The formation of an IS in T cells is triggered by stimulation of the T cell antigen receptor and depends on the rapid and polarized remodeling of the cytoskeleton. This dramatic change in cell polarity is required to achieve optimal T cell activation and function. In this chapter, we will ...
Vav1 has established roles in proliferation, cytokine secretion, Ca(2+) responses, and actin cytoskeleton regulation; however, its function in the regulation of phosphorylation of TCR components, including the ζ chain, the CD3 δ, ε, γ chains, and the associated kinases Lck and ZAP-70, is...
Phosphoinositide 3-kinase regulates glycolysis through mobilization of aldolase from the actin cytoskeleton. Cell 164, 433–446 (2016). Article CAS PubMed PubMed Central Google Scholar Giladi, A. & Amit, I. Single-cell genomics: a stepping stone for future immunology discoveries. Cell 172, 14...
ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation. During activation, T cells associate with antigen-presenting cells, a dynamic process that involves the formation of a broad area of intimate membrane contact known as the immunological synapse. The molecular intermediates that...
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Integrin-linked kinase (ILK) links integrins to the actin cytoskeleton and is believed to phosphorylate several target proteins. We report that a keratinoc... K Lorenz,C Grashoff,R Torka,... - 《Journal of Cell Biology》 被引量: 251发表: 2007年 IL-1 activity is reduced in psoriatic skin...