(2008) The actin cytoskeleton in T cell activation. Annu. Rev. Immunol. 26, 233-259 CrossRef PubMedBurkhardt JK, Carrizosa E, Shaffer MH. The actin cytoskeleton in T cell activation. Annu Rev Immunol 2008;26:233-259.Burkhardt JK, Carrizosa E, Shaffer MH. The actin cytoskeleton in T ...
Reorganization of the T-cell cytoskeleton is a rapid and dynamic process that is required to establish T-cell polarity and regulate cell–cell adhesion and T-cell activation. Actin polymerization leading to lamellipodium and distal-pole formation facilitates T-cell–antigen-presenting-cell (APC) rec...
The actin cytoskeleton seems to play two critical roles in the activation of T cells. One of these roles is T cell shape development and movement, including formation of the immunological synapse. The other is the formation of a scaffold for signaling components. This review focuses on the rece...
The integrated outcome of these signals depends on the cellular context in which the signal is received and may result in T cell activation, anergy, or apoptosis. A signal is generated when a peptide in the context of an MHC molecule engages the TCR complex. This binding interaction sets off...
How to Cite (2002), Dynamics of T-cell activation: shape change and the actin cytoskeleton (Biochemical Immunology Group). Immunology, 107: 29–30. doi: 10.1046/j.1365-2567.107.s1.58.x Publication History Issue published online: 9 DEC 2002 Article first published online: 9 DEC 2002 ...
Actin microfilaments form a three-dimensional cytoskeletal network throughout the cell and constitute an essential throughway for organelle and vesicle transport. Development of Arabidopsis trichomes, unicellular structures derived from the epidermis, is being used as a genetic system in which to study ...
Vascular endothelial growth factor C promotes cervical cancer metastasis via up-regulation and activation of RhoA/ROCK-2/moesin cascade Methods In this study, we investigated the effects of VEGF-C on actin cytoskeleton remodeling and on cervical cancer cell migration and invasion and how ... M He...
Cell motility is crucial for tissue formation and for development of organisms. Later on cell migration remains essential throughout the lifetime of the organism for wound healing and immune responses. The actin cytoskeleton is the cellular engine that drives cell motility downstream of a complex sig...
Actin cytoskeleton: Setting the pace of cell movement 来自 Elsevier 喜欢 0 阅读量: 24 作者: KBH Hartwig 摘要: Eukaryotic cells have many proteins that cap the barbed ends of actin filaments. Manipulation of their cellular concentration leads to changes in cell motility rates, actin dynamics ...
In combination, these compounds stimulate downstream pathways associated with T cell activation and have been extensively studied [55]. We evaluated specific subsets of cells from samples treated with ctrl and each respective perturbation. To account for interpatient variability in differential expression ...