Effect of local probiotic (Lactobacillus reuteri) vs systemic antibiotic therapy as an adjunct to non‐surgical periodontal treatment in chronic periodontitisantibioticschronic periodontitisLactobacillus reuteriprobioticsscaling and root planingAim: The aim of this study was to assess and compare the clinical...
These exploratory observations suggest that use of systemic anti-inflammatory therapy in this manner, as is done for a wide variety of diseases, is unlikely to induce large amounts of systemic adverse effect morbidity at least over a period of up to 7 years. Limitations This study has several...
We started by checking several organs known to be sensitive to radiation to confirm the irradiation method and to analyse the effect of radiation on the whole body. The thymus, which is highly sensitive to radiation in both mammals and medaka, is situated in the medaka on both sides of the...
As described before, DNase is known as a highly effective and well-tolerated mucolytic agent in CF. When gelsolin was added to DNase 1 treatment, a synergistic effect was observed, resulting in a two-fold higher rate of sputum fluidization [104]. This is supported by the observation that gel...
The overall fixed-effect OR was 0.69 (95% CI, 0.55-0.86) among patients who were receiving invasive mechanical ventilation at randomization (corresponding to an absolute risk of 30% for corticosteroids vs 38% for usual care or placebo) and the OR was 0.41 (95% CI, 0.19-0.88) among ...
However, no relevant data regarding the effect of SII on ISR after DES-based PCI is known. The present study offered a timely opportunity to evaluate the dose-response relationship between SII and ISR, revealing that SII was also an independent risk factor for DES-ISR in patients with ACS. ...
3 These subtypes are further specified according to the extent of their skin involvement (local vs. generalized), morphology, and localization of the inflammatory infiltrate in the skin (e.g., LE panniculitis indicating LE-specific infiltration of adipose tissue). It is important to note that in...
One major effect of type I IFNs is to increase the cytotoxicity of NK cells and T CD8+ cytotoxic lymphocytes. ‘NK cells’ are neither B nor T lymphocytes and constitute 5–15% of the mononuclear cells in the blood and spleen. They distinguish infected and injured cells from healthy cells...
Interestingly, mice with only ligatures (N + Lig group) also showed higher histological scores than mice without any treatment. How periodontitis causes this intestinal damage may be explained by the effect of experimental periodontitis on systemic inflammation. It has been reported that experiment...
therapeutically.slc15a4feeblemice, lacking pDC sensing, exhibited attenuated local and systemic IMQ effects compared to WT mice. It is also possible that the effect ofslc15a4deficiency is mediated in part via B cells. However, this is less likely as the reported effects ofslc15a4deficiency in ...