In contrast, local application of gentamicin delivered from a PDLLA coating was more effective. Onset of infection could be prevented in 90% of animals treated with gentamicin coated Kirschner wires, and in 80% of the animals that were treated with a combination of local and systemic application...
ObjectiveAnalysis of systemic and local odontogenic infection complications requiring hospital care.MethodsAll cases of odontogenic infections requiring hospital care, which were adjudicated in the Finnish Patient Insurance Centre during 2000–2003, were analysed. Patient characteristics, and the course and ou...
Patients were classified as systemic infection (n = 88) or isolated pocket infection (n = 68). Prospectively collected preoperative procalcitonin (PCT), C-reactive protein, and white blood cell count were compared between groups. Pairwise comparisons revealed that the systemic infection group had a...
Systemic acquired resistance (SAR) is a long-lasting broad-spectrum plant defense mechanism induced in distal systemic tissues by mobile signals generated at the primary infection site. Despite the discoveries of multiple potential mobile signals, how these signals cooperate to trigger downstream SAR sig...
Systemic antibiotic treatment is widely used in several infectious diseases, such as chronic osteomyelitis, bacterial endophthalmitis, airway infection, and acne. However, the use of antibiotics can cause gut dysbiosis.4,5The intestinal microbiota is the most diverse and largest bacterial population in ...
Acute inflammation is characterized by the accumulation of leukocytes, plasma proteins (e.g., complement components), and fluid derived from the blood at a site of infection or injury. Neutrophils and macrophages are recruited, a process known as ‘chemotaxis,’ under the control of TNFα, IL-...
It was proposed that the normal response to local infection or tissue injury was to produce a local inflammatory reaction, attracting effectors phago- cytes at the site of injuries or infection [11]. In contrast, an excess of anti-inflammatory mediators (soluble TNF © 2012 Pugin; licensee ...
Hospitalizations for infection were infrequent in both the implant and the systemic therapy groups (9 hospitalizations vs 6, respectively). Change in weight did not significantly differ between the groups (eFigure 2 in Supplement 1). Bone marrow suppression and indicators of liver or renal injury ...
Systemic acquired resistance: turning local infection into global defense. Annu. Rev. Plant. Biol. 64, 839–863 (2013). Article CAS Google Scholar Kehr, J. & Buhtz, A. Long distance transport and movement of RNA through the phloem. J. Exp. Bot. 59, 85–92 (2008). Article CAS ...
Similar to tattooing, local infection may occur with abscess formation.264–267 The most frequent pathogens encountered are Staphylococcus aureus, Streptococcus pyogenes, and Pseudomonas aeruginosa.261 Both piercing and tattooing histopathologically may result in foreign-body reactions to the inorganic ...