Reduced production of the beta subunitand thus reduced adult hemoglobin levels in the blood can cause beta-thalassemia. Depending on the type of mutation, beta-thalassemia is typically classified as [5,1]: Beta-Thalassemia Major Also known asCooley’s AnemiaandMediterranean Anemia Characterized by h...
The gene for beta thalassemia is not evenly distributed among different groups of people. It is, for example, relatively more frequent in people of Italian and Greek origin, both of whom are people from the Mediterranean. Because of this, thalassemia major has been called Mediterranean anemia. T...
The gene for beta thalassemia is not evenly distributed among different groups of people. It is, for example, relatively more frequent in people of Italian and Greek origin, both of whom are people from the Mediterranean. Because of this, thalassemia major has been called Mediterranean anemia. T...
Introduction Beta thalassemia major (BTM) is a chronic hereditary blood disorder. Patients are dependent on blood transfusion and are prone to multiple comorbidities. Depression, anxiety, and stress (DAS) can complicate their condition. No reports from Saudi Arabia to measure DAS in BTM patients. ...
The symptoms may range from moderate to severe in case of three mutated genes. This type of the disorder is also known as Hemoglobin H disease. In case of four mutated genes, the disease is referred to as Hydrops fetalis or Alpha-Thalassemia Major. It generally leads to the death of a ...
ThalassemiaRadiotherapy DosageAdolescentAdultEvaluation Studies as TopicBone Marrow TransplantationMiddle AgedExtramedullary hemopoiesis or marrow heterotopia (MH) occurs in about 15% of cases of thalassemia major or intermedia [6, 8, 9]. It also occurs in myelosclerosis and in other chronic anemic......
Thalassemia happens with a problem with hemoglobin formation (four chains aren't correctly formed). You make really small red blood cells, though you can make enough of them to be asymptomatic, or it can be severe. It’s passed down in your genes and usually affects people of Mediterranean,...
The etiology of primary hemochromatosis is unknown. It is described a secondary form, which occurs when the body is overload with iron: red blood cells diseases (sideroblastic anemia, thalassemia major), oral ingestion of iron, liver disease (alcoholic cirrhosis, porphyria cutanea tarda). There ...
Small doses of radiotherapy (10 to 26 Gy) relieved symptoms in all of them. 3 of the patients were followed-up radiographically. In 2 the mass of heterotopic marrow regressed completely and in the other partially.关键词: Humans Dyspnea Spinal Cord Compression Thalassemia Radiotherapy Dosage ...
Hemoglobin E–thalassemia disease (one gene for Hb E, one gene for thalassemia) is severe and clinically closely resembles thalassemia major. Hemoglobin H, found in many groups in the Old World (e.g., Chinese, Thai, Malayans, Greeks, Italians), has almost always been identified in ...