Find out more about Leica super-resolution microscopy solutions and how they can empower you to visualize in fine detail subcellular structures and dynamics.
Microscopy: Isotropic super-resolution imagingThe article discusses the development of the direct optical nanoscopy with axially localized detection (DONALD) to bypass axial resolution diffraction limitation in improving late...
Super-resolution imaging for cell biologists: concepts, applications, current challenges and developments. Bioessays 37, 436–451 (2015). Article PubMed Google Scholar Turkowyd, B., Virant, D. & Endesfelder, U. From single molecules to life: microscopy at the nanoscale. Anal. Bioanal. ...
Super-resolution imaging of fast morphological dynamics of neurons in behaving animals A variant of structured illumination microscopy called MLS-SIM allows super-resolution imaging of neuronal structures such as spinules, spines and boutons in awake mice. Yujie Zhang , Lu Bai & Kai Wang Article...
PALMIRA Superresolution Imaging An advanced single-molecule technique that avoids several potential artifacts. Structured Illumination Microscopy Patterned excitation for optical sectioning forms the basis for superresolution. Selective Plane Illumination An emerging technique with great potential for superresolution...
According to the dual-color SMLM imaging of exosomes and lysosomes, we confirmed that exosomes can be transported into lysosomes for further degradation after binding to recipient cells. Moreover, as one kind of the natural carriers of the cellular cargoes, exosomes can encapsulate mir-21 inside ...
Fluorescence bio-imaging has been used to study cell biology for decades. However, the structures and functions of the subcellular organelles which fall under the diffraction limit are still not explored fully at a nanoscale level. Several super-resolution microscopy (SRM) techniques have been ...
Photoactivated localization microscopy (PALM) and the related technique of Stochastic optical reconstruction microscopy (STORM) are super-resolution imaging methods based on the precise localization of single molecules. Instruments based on these techniques are now commercially available and are capable of ge...
Super-resolution microscopy (SRM) describes a number of microscopy techniques that enable imaging of cellular structures at resolutions beyond the Abbe diffraction limit. Nano-Boosters, Nano-Labels, and Nano-Secondaries, which consist of Nanobodies conju
Despite tremendous improvements in microscopy, there still exists a remarkable gap betweenresolutionin all three dimensions. One of the methods that can close this gap and achieves a resolution in the nanometer range is metal-inducedenergy transfer(MIET) imaging. The exceptional depth resolution of MI...