aif party Bwants to terminate this contract,he must hand in a written application one month before leaving China. 如果党终止这个合同的Bwants,他在一种书面应用必须递一个月在离开中国之前。[translate] asubstrate-specific transporter activity 基体具体运输者活动[translate]...
The adaptive regulation is not associated with any change in the dependence of the transporter activity on Na+ and Cl-, in the Na+/Cl-/taurine stoichiometry and in the affinities of the transporter for Na+ and Cl-. The decrease in the transporter activity caused by taurine exposure is due...
3α-HSD also converts bile acid precursors to bile acids and may serve as a bile acid transporter in the liver and intestine(11, 12). 3α-HSD in the liver is responsible for inactivation of steroid hormones and maintenance of the homeostatic balance of circulating steroid hormones. ...
D. et al. Structural basis of gating by the outer membrane transporter FecA. Science 295, 1715–1719 (2002). 56. Krieg, S. et al. Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex. Proc. Natl Acad. Sci. USA 106, 1045–1050 (...
Imatinib Mesylate Is a Potent Inhibitor of the ABCG2 (BCRP) Transporter and Reverses Resistance to Topotecan and SN-38 in Vitro Imatinib mesylate (Gleevec, STI571) is a kinase inhibitor selective for Bcr-Abl, activated c-Kit kinases, and platelet-derived growth factor receptor tyros... PJ Ho...
The enzyme shows peroxidase activity in the presence of H2O2. It is unexpected because H2O2 generation is related to the Fenton reaction, and many involved genes were down-regulated in wood wafers. However, we also observed that two aryl-alcohol oxidase genes (CAZy: AA3_2, Fibra1|8187, ...
Further, we consider it likely that such long hydrophilic N-termini interact with the positively charged internal loops of the transporter itself or with neighboring transporters and thereby are involved in regulation of activity. In line with this hypothesis, the Saccharomyces cerevisiae general amino ...
cystine/glutamate transporterinterleukin 1 (IL-1)mRNA stabilityneuroinflammationpost-transcriptional regulationsystem xc-System xc(-) is a heteromeric amino acid cystine/glutamate antiporter that is constitutively expressed by cells of the CNS, where it functions in the maintenance of intracellular ...
Molecular cloning and characterization of a human multisubstrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection - Suda, Kamiyama, et al. - 2004 () Citation Context ...for NSTs that exhibit UDP-GlcNAc transport activity as singular or one of multispecificities (Abei...
Both GIu300Asp and Glu389Asp had lowered affinity to TEA, whereas the affinity of Glu389Asp to cimetidine was fourfold higher than that of the wild- type transporter with about a fourfold decrease in Vmax value. Both Glu273Asp and Glu300Asp had altered pH dependence for TEA uptake. These ...