This study investigates the effects of MOTS-c treatment in a mouse model of type 1 diabetes-induced DCM.#Type 1 diabetes (T1DM) was induced in mice by streptozotocin (STZ) injection. After diabetes establishment, the mice were randomly dividend into two groups treated with or without MOTS-c ...
5.Single-cell RNA sequencing analysis reveals the relationship of bone marrow and osteopenia in STZ-induced type 1 diabetic mice 6.Activated AMPK mitigates diabetes-related cognitive dysfunction by inhibiting hippocampal ferroptosis. 7.Protective effects of sulforaphane on type 2 diabetes-induced cardiomyop...
[10] Marino F, et al. Streptozotocin-Induced Type 1 and 2 Diabetes Mellitus Mouse Models Show ...
Here, using a streptozotocin (STZ)-induced preclinical T1D mouse model, we found that iTregs could ameliorate the development of T1D and preserve β cell function. The preventive effect was associated with the inhibition of type 1 cytotoxic T (Tc1) cell function and rebalancing the Treg/Tc1...
In addition to the STZ-induced T1D model, nonobese diabetic (NOD) mouse, BioBreeding/Worcester rat, and lymphocytic choriomeningitis virus-induced model could also represent T1D animal models [51]. We limited our model in this research to STZ-induced T1D mice only. This limitation may result...
induced Tregs (iTregs) in T1D remain poorly understood. Here, using a streptozotocin (STZ)-induced preclinical T1D mouse model, we found that iTregs could ameliorate the development of T1D and preserve β cell function. The preventive effect was associated with the inhibition of type 1 ...
Fig.6 The liver biopsy of diabetic mouse 注射链脲佐菌素18 d后解剖小鼠观察胰岛,40 mg/Kg组:2只小鼠内(哪?)分别(不规 范)8个4个胰岛(分别+或??下面用词一样需要修改),体积较小,胰岛周围或胰岛内 未见炎细胞浸润;50 mg/Kg组: 2只小鼠内分别查见2个或6个胰岛,中等大小,胰岛周 围或胰岛内未见炎...
Pathogenesis of mouse diabetes mellitus models induced by different doses of streptozotocin YANG Wei 1 ,LUO Chun‐yuan 1 ,YU Chun‐lei 1 ,WANG Li 1 ,XU Li‐fang 2 ,LI Yi 1倡 (1 .Department of Immunology ,School of Basic Medical Sciences ,Jilin University ,Changchun 130021 ,China ; ...
Moreover, camel whey protein supplementation in a streptozotocin-induced type 1 diabetic mouse model has been reported to have beneficial antidiabetic effects by decreasing the free radicals, enhancing antioxidant levels, and orchestrating redox status, hence restoring blood glucose and insulin levels. ...
formosana on Type I diabetes and hyperglycemia-induced depression. OFE were found to promote the expression of adiponectin, which is an adipokine involved in insulin sensitivity and hold anti-depressive effects. In addition, OFE administration also displayed altered levels of neurotransmitters in ...