The structure provides the first insight into the molecular architecture of TSPO/PBR protein family that will serve as a framework for future studies.Vladimir M. Korkhov and Carsten Sachse and Judith M. Short and Christopher G. TateStructure...
Protein Structure+ Levels of Protein Structure Amino Acid Properties and Structure Protein Synthesis Protein-Protein Interation Protein-Ligand Interation Protein Stability and Dynamics Protein Function Protein Folding Protein Phosphorylation Post-Translational Modifications: Types, Functions, and Analytical Methods ...
The exact pore-forming structure of the mPT remains controversial. The voltage-dependent anion channel (VDAC) [22], proapoptotic Bcl-2 family members (Bax and Bak) [9,23,24,25], the phosphate carrier (PiC) [26] and the translocator protein (TSPO) [27] had been proposed to contribute t...
Trans- locator proteins (TSPO) modulate storage lipids and cytoplasmic lipid droplet metabolism in seeds of Arabi- dopsis [52]. DDB1-CUL4 Associated Factor homologue 1 (DCAF1) is essential for plant embryogenesis, and reduced levels lead to various developmental defects [53]. The serine/...
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(partition protein B)preads along the chromosomal DNA and a high-order complex isequired for this function.Although ParB spreading has beentudied,the detailed mechanism is still unclear.Herein,we reporthe crystal structure of the C-terminal domain truncated proteinCt-HpSpo0J)-parS complex and ...
(TSPO) modulate storage lipids and cytoplasmic lipid droplet metabolism in seeds ofArabidopsis[52]. DDB1-CUL4 Associated Factor homologue 1 (DCAF1) is essential for plant embryogenesis, and reduced levels lead to various developmental defects [53]. The serine/threonine protein kinase Constitutive ...
Ttranslocator protein (TSPO) is ubiq-uitous throughout our bodies. It transports cholesterol and other molecules across the membranes of mitochondria-the power stations inside our cells-and has also been implicated in Alzheimer's disease, various cancers and cardiovascular disease. But scientists are...
Cholesterol is an important regulator of membrane protein function. However, the exact mechanisms involved in this process are still not fully understood. Here we study how the tertiary and quaternary structure of the mitochondrial translocator protein TSPO, which binds cholesterol with nanomolar affinity...
H. Shen, et al. (2013). Reconstitution of Membrane Proteins into Model Membranes: Seeking Better Ways to Retain Protein Activities. Int. J. Mol. Sci.,14: 1589-1607. A. Zeltins et al., (2013). Construction and characterization of virus-like particles: a review. Mol Biotechnol.,53(1)...