TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastomaTSPOGBAnti-tumor immunityImmune-resistanceTRAIL-resistanceGlioblastoma (GB) IDH-wildtype is the most malignant
Aberrant immune responses including reactive phagocytes are implicated in the etiology of age-related macular degeneration (AMD), a major cause of blindness in the elderly. The translocator protein (18 kDa) (TSPO) is described as a biomarker for reactive gliosis, but its biological functions ...
The db/db mouse model is a polygenic model that is caused by a mutation in the leptin receptor gene, which is not the primary genetic cause of type 2 diabetes in humans. Additionally, the db/db mouse model may not replicate all of the pathological changes seen in human DR, such as ...