Its full form isRibonucleic acid. This is a polymer of subunits joined by phosphodiester bonds. It is a single-stranded nucleic acid similar to DNA but having ribose sugar rather than deoxyribose sugar and uracil instead of thymine as one of the nucleotide bases. Figure: Types of RNA. Image ...
RNA is involved in many cellular processes such as control of gene expression, catalysis of various substrates, scaffolding of complex assemblies, and molecular chaperoning15. Its ability to act as a hub of cellular networks is at the centre of an active research field and has already led to t...
RNAs perform their function by forming specific structures, which can change across cellular conditions. Structure probing experiments combined with next generation sequencing technology have enabled transcriptome-wide analysis of RNA secondary structure
Learn what the two main types of nucleic acids are, what they are made of, and why they are so important to every living thing on the planet. Related to this QuestionCompare and contrast the structure of DNA and RNA. Compare and contrast DNA and RNA. Compare and contrast DNA and RNA ...
of genetic information, whereas the relative instability of RNA makes it more suitable for its more short-term functions. The RNA-specific pyrimidineuracilforms a complementary base pair with adenine and is used instead of the thymine used in DNA. Even though RNA is single stranded, most types ...
Reciprocally, the identification and characterization of known and novel RNA motifs are greatly advanced by the structure determination of new types of large biological RNAs. In this review, recent structure determinations of several biological RNAs are presented and described. The secondary structure and...
The process of RNA editing can occur in various types of RNA molecules, including pre-mRNA, mature mRNA, miRNA, lncRNA, tRNA, and even viral RNA [11,12,13]. An important impact of RNA editing is its ability to challenge the central dogma of biology. When RNA editing takes place in th...
RNA structure is intimately connected to each step of gene expression. Recent advances have enabled transcriptome-wide maps of RNA secondary structure, called ‘RNA structuromes’. However, previous whole-cell analyses lacked the resolution to unravel th
Structures can occur in coding or non-coding RNAs, and learning more about RNA structure will improve our understanding of the transcriptome. Computational predictions of RNA structures have been important and continue to be refined and also combined with experimental methods. Experimental methods, which...
2.2A), except for those subunits at the very ends of the helix. Each capsid molecule binds three nucleotides of RNA within a groove in the protein. The helix has a pitch of 23 Å and there are 161/3 subunits per turn of the helix. The length of the TMV virion (300nm) is ...