RNAs can also form complexes with molecules known asribonucleoproteins (RNPs). The RNA portion of at least one cellular RNP has been shown to act as a biologicalcatalyst, a function previously ascribed only to proteins. Types and functions of RNA ...
rRNA and tRNA are stable types of RNA. In prokaryotes and eukaryotes, tRNA and rRNA are encoded in the DNA, then copied into long RNA molecules that are cut to release smaller fragments containing the individual mature RNA species. In eukaryotes, synthesis, cutting, and assembly of rRNA into ...
此研究确定了已知的和以前未被描述的对恐惧学习有反应的候选基因,其中的分子图谱可以用来揭示调节学习和记忆的情绪成分的神经元类型和神经回路。相关工作已发表在Nature Neuroscience上,题目为“Neuronal types in the mouse amygdala and their transcriptional response to fear conditioning”。 首先,他们对23只成年小鼠(...
Structural characterization and catalytic mechanism of cytosine deaminase.AOrganization of domains in cytosine deaminases.BThe structure of core deaminase domains. (APOBEC1 PBD: 6 × 91, APOBEC3A PDB: 5KEG and APOBEC3G PDB: 6BUX)CThe deaminase function of APOBEC1 depends on its binding to ...
Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis Biochemistry, 36 (1997), pp. 16345-16354 View in ScopusGoogle Scholar Jacks 1990 T Jacks Translational suppression in gene expression in retroviruses ...
[4] G.M. Cheetham, T.A. Steitz, Insights into transcription: structure and function of single-subunit DNA-dependent RNA polymerases, Current opinion in structural biology 10 (2000) 117-23. [5] P.A. Pavco, D.A. Steege, Characterization of elongating T7 and SP6 RNA polymerases and their...
摘要: The versatility of RNA structure and function. Jacques Monod Conference: New insights into the mechanism of mRNA translation: the significance of RNA structure, Aussois, France, 22-26 March 1999. - ResearchGateDOI: 10.1016/S0168-9525(99)01779-5 ...
The more researchers examine RNA, the more surprises they continue to uncover. What have we learned about RNA structure and function so far? AaAaAa Figure 1 Figure Detail With the discovery of the molecular structure of theDNAdouble helixin 1953, researchers turned to the structure ofribonucleic...
However, in the half-century sincethe structure of DNA was first elaborated, scientists have learned that RNA does much more than simply play a role in protein synthesis. For example, many types of RNA have been found to be catalytic--that is, they carry out biochemical reactions just like...
the sites ofproteinsynthesisin thecytoplasm(theribosomes). The molecule that would eventually become known as mRNA was first described in 1956 by scientists Elliot Volkin and Lazarus Astrachan. In addition to mRNA, there are two other major types ofRNA:ribosomal RNA(rRNA) andtransfer RNA(tRNA)...