Some types of mRNA are specific for certain types of cells, which encode for the proteins that are needed for the function of that particular cell such as mRNA for hemoglobin is found in Red Blood Cells (RBCs). Figure: Prokaryotic and Eukaryotic Messenger RNA (mRNA). Image Source:ScienceDire...
rRNA and tRNA are stable types of RNA. In prokaryotes and eukaryotes, tRNA and rRNA are encoded in the DNA, then copied into long RNA molecules that are cut to release smaller fragments containing the individual mature RNA species. In eukaryotes, synthesis, cutting, and assembly of rRNA into ...
The versatility of RNA structure and function. Jacques Monod Conference: New insights into the mechanism of mRNA translation: the significance of RNA structure, Aussois, France, 22-26 March 1999. - ResearchGate P Linder,MF Tuite - 《Trends in Genetics Tig》 被引量: 6发表: 1999年 The versatil...
此研究确定了已知的和以前未被描述的对恐惧学习有反应的候选基因,其中的分子图谱可以用来揭示调节学习和记忆的情绪成分的神经元类型和神经回路。相关工作已发表在Nature Neuroscience上,题目为“Neuronal types in the mouseamygdalaand their transcriptional response to fear conditioning”。 首先,他们对23只成年小鼠(其中...
The in vivo folding of RNA structure is tightly associated with its function and largely dependent on the cellular context [1, 2]. Because of the complexity within living cells, RNA folding in vivo could be very different from that in vitro [3, 4]. For many complex RNA structures, althoug...
structures makes it a potential ADAR substrate, and A-to-I editing can influence the stability and function of lncRNA by altering the structure of lncRNA and its interaction with miRNA [53]. This suggests a connection between RNA editing and gene silencing in terms of impeding gene regulation...
RNAs can also form complexes with molecules known asribonucleoproteins (RNPs). The RNA portion of at least one cellular RNP has been shown to act as a biologicalcatalyst, a function previously ascribed only to proteins. Types and functions of RNA ...
However, in the half-century sincethe structure of DNA was first elaborated, scientists have learned that RNA does much more than simply play a role in protein synthesis. For example, many types of RNA have been found to be catalytic--that is, they carry out biochemical reactions just like...
Although long non-coding RNAs (lncRNAs) and mRNAs share many common features, several types of lncRNAs are distinguished from mRNAs by unique features of biogenesis, form and function. lncRNAs exhibit more highly specific expression patterns than mRNAs. Many lncRNAs undergo special processing events, ...
telomerase (Gilley & Blackburn, 1999), and in viral genomic RNAs (for a review, see ten Dam et al., 1992). An RNA pseudoknot is a structural element of RNA which forms when nucleotides within one of the four types of single-stranded loops in a secondary structure (hairpin loop, bulge ...