Antigenic structure of the influenza B virus hemagglutinin: nucleotide sequence analysis of antigenic variants elected with monoclonal antibodies - BERTON, NAEVE, et al. - 1984 () Citation Context ... of the most antigenic sites for the influenza virus HA protein. The variati...
To study the mechanism of antigenic drift in influenza B viruses, monoclonal antibodies were used to select antigenic variants of B/Hong Kong/8/73 virus hemagglutinin (HA). Analyses of the nucleotide sequences of the HA gene of B/Hong Kong/8/73 and the eight variants identified specific ...
Abstract The haemagglutinin glycoprotein of influenza virus is a trimer comprising two structurally distinct regions: a triple-stranded coiled-coil of α-helices extends 76 Å from the membrane and a globular region of antiparallel β-sheet, which contains the receptor binding site and the variable...
Integrating computational modeling and functional assays to decipher the structure-function relationship of influenza virus PB1 protein Chunfeng Li1,2*, Aiping Wu2,3*, Yousong Peng4, Jingfeng Wang2, Yang Guo5, Zhigao Chen1, Hong Zhang3, Yongqiang Wang3, Jiuhong Dong3, Lulan Wang1, F. ...
Crystal Structure of Human ISG15 Protein in Complex with Influenza B Virus NS1 B.doi:10.1074/jbc.C111.257899ISG15 (interferon-stimulated gene 15), the first ubiquitin-like protein (UBL) identified, has emerged as an important cellular antiviral factor. It consists of two UBL domains with a ...
B. (1995). Isolation and structure of fluti- mide, a novel endonuclease inhibitor of influenza virus. Tetrahedron Lett. 36, 2005-2008.Singh, S.B. (1995) Total synthesis of f1utimide, a novel endonuclease inhibitor of influenza virus. Tet Lett 36: 2009-2012....
Morphology of particle/virus familyEnvelopedTriangulation numberMorphology of nucleocapsidFigure numbers Icosahedral Adenoviridae No T = 25 Not applicable Figs. 2.1, 2.12 Reoviridae No T = 13l a Icosahedral Figs. 2.1, 2.5, 2.11 Papillomaviridae No P = 7d a,b Not applicable Figs. ...
The structure of the haemagglutinin‐esterase‐fusion (HEF) glycoprotein from influenza C virus has been determined to 3.2 resolution by X‐ray crystallography. A synthetic mercury‐containing esterase inhibitor and receptor analogue, 9‐acetamidosialic acid α‐thiomethylmercuryglycoside, was designed as ...
pieces.Forexample,bothinfluenzavirusandrotavirus haveasegmentedRNAgenome.Almostallviruses containonlyasinglecopyoftheirgenome;ie,theyare haploid.Theexceptionistheretrovirusfamily,whose membershavetwocopiesoftheirRNAgenome;ie, theyarediploid. VIRALCAPSID&SYMMETRY ...
Molecular basis of the structure and function of H1 hemagglutinin of influenza virus Influenza virus hemagglutinin (HA) contains antigenic sites recognized by the host immune system, cleavage sites cleaved by host proteases, receptor bindin... NS Suzuki - 《Proceedings of the Japan Academy》 被引量...