Influenza A viruses (IAVs) constitute a major threat to human health. The IAV genome consists of eight single-stranded viral RNA segments contained in separate viral ribonucleoprotein (vRNP) complexes that are packaged together into a single virus particle. The structure of viral RNA is believed ...
The structure of the influenza A virus genome.doi:10.1038/S41564-019-0513-7Bernadeta DadonaiteBrad GilbertsonMichael L KnightSanja TrifkovicSteven RockmanAlain LaederachLorena E BrownErvin FodorDavid L V BauerNature Publishing Group
Electron microscopy of influenza virus. Credit: CDC A team of researchers from the U.K., Australia and the U.S. has mapped the structure of the influenza A virus genome. In their paper published in the journalNature Microbiology, the group describes their genetic analysis of the virus and w...
2008. Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design. FASEB J 22:3638 -3647. http://dx .doi.org/10.1096/fj.08-112110.Ng AK, Zhang H, Tan K, Li Z, Liu JH, Chan PK, et al. Structure of the influenza virus A...
et al. The structure of the influenza A virus genome. Nat. Microbiol. 4, 1781–1789 (2019). Article CAS PubMed PubMed Central Google Scholar Le Sage, V. et al. Mapping of influenza virus RNA-RNA interactions reveals a flexible network. Cell Rep. 31, (2020). Weidmann, M. et al....
[advances in virus research] advances in virus research volume 63 volume 63 || novel insights into hepatitis c virus replication and persistence R Bartenschlager 被引量: 11发表: 2004年 [Advances in Virus Research] Volume 66 || In A Nutshell: Structure and Assembly of the Vaccinia Virion ...
Virus particles, called virions, contain the viral genome encapsidated in a protein coat. The function of the coat is to protect the genome of the virus in the extracellular environment as well as to bind to a new host cell and introduce the genome into it. Viral genomes are small and ...
The influenza viruses are characterized by segmented, negative-strand RNA genomes requiring an RNA-dependent RNA polymerase of viral origin for replication. The particular structure of the influenza virus genome and function of its viral proteins enable antigenic drift and antigenic shift. These processes...
Influenza A viruses (IAV) are a prevalent respiratory pathogen that can cause seasonal flu and global pandemics, posing a significant global public health threat. Emerging research suggests that IAV infections may disrupt the balance of gut microbiota, w
structureSummary Influenza virus gene expression and genome replication are mediated by the viral polymerase, composed of proteins PB1, PB2, and PA, and the viral nucleoprotein NP. The pb1 gene also encodes an internal open reading frame for the protein PB1-F2, a potential regulator of ...