Dynamic nanomechanical properties of bovine bone marrow stromal cells (BMSCs) and their newly synthesized cartilage-like matrices were studied at nanometer scale deformation amplitudes. The increase in their dynamic modulus, |E⁎| (e.g., 2.4±0.4kPa at 1Hz to 9.7±0.2kPa at 316Hz at day 21...
Introduction to Stromal Cells Originally described as noncancerous cells within a tumor,stromal cellsare now typically defined asconnective tissue cellsof an organ. Stroma is comprised of theextracellular matrixand a number of cell types, including mesenchymal cells such as fibroblasts andpericytes, as...
I Aizman, CC Tate, M McGrogan, et al., Extracellular matrix produced by bone marrow stromal cells and by their derivative, SB623 cells, supports neural cell growth, J Neurosci Res, 87, 3198 (2009).Extracellular matrix produced by bone marrow stromal cells and by their derivative, SB623 ...
由内皮,成纤维细胞,网状细胞,脂肪细胞和巨噬细胞组成。提供住宿并发布短期生长因子。 Matrix of adherent multilayered cellular complex that provides the microenvironment for hematopoiesis. Composed of endothelium, fibroblasts, reticular cells, fat cells, and macrophages. Furnishes lodging and issues short-range...
In order to understand the relationship of marrow stromal cells, hematopoietic growth factors and extracellular matrix proteins we studied mRNA expression in adherent long term marrow culture (LTMC) cells and Simian Virus-40 (SV40) transformed stromal cells. Results indicate that M-CSF and TGFβ 1...
Adipose derived stromal cells (ADSC) are relevant therapeutic agents to treat myocardial infarction (MI) in clinical trials. Soluble factors secreted by ADSC, such as growth factors and cytokines, suppress inflammation and apoptosis while promoting angiogenesis and the proliferation of cardiomyocytes (CM...
Mesenchymal/stromal stem cells (MSCs) are a crucial component of the tumour microenvironment (TME). They can be recruited from normal tissues into the TME and educated by tumour cells to transform into tumour-associated MSCs, which are oncogenic cells that promote tumour development and progression...
periostin as well as matrix metalloproteinase-1 and -3 in stromal cells and lung tissueswere examined with quantitative real-time reverse transcriptase polymerase chain reactionand immunohistochemistry, respectively. Twenty genes were similarly up- or down-regu-lated in IPF and ADC compared to control,...
Autologous bone marrow stromal cells (BMSCs) infusion therapy improves the hepatic fibrosis. To investigate the mechanism of remission, we evaluated the matrix metalloproteinase (MMP)-2 and -9 activity in canine BMSCs and the effect of pro-inflammatory cytokines on their expression. The activity ...
Adipose Extracellular Matrix/Stromal Vascular Fraction Gel: A Novel Adipose Tissue-Derived Injectable for Stem Cell Therapy 来自 掌桥科研 喜欢 0 阅读量: 513 作者:Y Yao,Z Dong,Y Liao,P Zhang,J Ma,J Gao,F Lu 摘要: BACKGROUND: Adipose-derived stem cells and other stromal vascular fraction ...