Gronthos S,Simmons PJ,Graves SE,et al.Integrin-mediated interactions between human bone marrow stromal precursor cells and the extracellular matrix. Bone . 2001Gronthos S, Simmons PJ, Graves SE, Robey PG. Integrin-mediated interactions between human bone marrow stromal precursor cells and the ...
Introduction to Stromal Cells Originally described as noncancerous cells within a tumor,stromal cellsare now typically defined asconnective tissue cellsof an organ. Stroma is comprised of theextracellular matrixand a number of cell types, including mesenchymal cells such as fibroblasts andpericytes, as...
Mesenchymal/stromal stem cells (MSCs) are a crucial component of the tumour microenvironment (TME). They can be recruited from normal tissues into the TME and educated by tumour cells to transform into tumour-associated MSCs, which are oncogenic cells that promote tumour development and progression...
Disclosed in the present invention is a method for in vitro screening, activation, proliferation, and cryopreservation of mesenchymal stromal/stem cells an... B Zhang,M Chen 被引量: 0发表: 2021年 加载更多来源期刊 国际眼科杂志:英文版 研究点推荐 extracellular matrix synthesis Cell viability corneal...
Trans-differentiation of hypertrophic chondrocytes into cells capable of producing a mineralized bone matrix. Bone Miner. 19, 1–20 (1992). Article CAS PubMed Google Scholar Decker, R. S. et al. Cell origin, volume and arrangement are drivers of articular cartilage formation, morphogenesis and...
Synthetic extracellular matrix mimic hydrogel improves efficacy of mesenchymal stromal cell therapy for ischemic cardiomyopathy Background: Mesenchymal stromal cells (MSC) repair Ciuffreda,Maria,Chiara,... - 《Acta Biomaterialia》 被引量: 3发表: 2018年 Advances in mesenchymal stromal cell therapy in ...
it can restrict the therapeutic response to chemotherapy. Together with the extracellular matrix, a variety of cell types in the TME, including pancreatic stellate cells (PSCs), cancer associated fibroblasts (CAFs), endothelial cells, and immune cells, form a dynamic microenvironment that can promote...
Mesenchymal/stromal stem cells (MSCs) are a crucial component of the tumour microenvironment (TME). They can be recruited from normal tissues into the TME and educated by tumour cells to transform into tumour-associated MSCs, which are oncogenic cells that promote tumour development and progression...
functions and actively cross-talks with cancer cells. These CAF cells can promote tumor cell growth, angiogenesis and invasion by secreting pro-inflammatory factors, chemokines, growth factors, remodeling of extracellular matrix and other paracrine factors . It can also promote regulatory immune cells ...
Autoimmune hepatitis is a chronic inflammatory hepatic disorder with no effective treatment. Mesenchymal stromal cells (MSCs) have emerged as a promising treatment owing to their unique advantages. However, their heterogeneity is hampering use in clinica