lymph node stromal cells (LNSCs). Advances in the last decade have expanded our understanding and appreciation of LNSC heterogeneity, and the role they play in coordinating immunity has grown rapidly. In this review, we will highlight the functional contributions of distinct stromal cell populations...
Lymph node stromal cells strongly influence immune response suppression. Eur J Immunol. 2011;41(3):624-633.Buettner M, Pabst R, Bode U. Lymph node stro- mal cells strongly influence immune response suppression. Eur J Immunol. 2011;41(3):624-633....
Stromal cells in lymph node attract B-lymphoma cells via production of stromal cell-derived factor-1. Eur J Haematol 2000;64:323-32.Arai J, Yasukawa M, Yakushijin Y, Miyazaki T, Fujita S. Stromal cells in lymph nodes attract B-lymphoma cells via production of stromal cell-derived factor-...
regulatory T cells. Mesenteric lymph node stromal cell-derived extracellular vesicles contribute to peripheral de novo induction of Foxp3+ regulatory T cells.Mesenteric lymph node stromal cell-derived extracellular vesicles contribute to peripheral de novo induction of Foxp3+ regulatory T cells.doi:...
This structure is provided by lymph node stromal cells, which also provide the lymphocytes with a scaffold upon which to migrate. Here, we discuss how stromal cells differentiate from mesenchymal precursor cells in response to the interaction with lymphocytes, while these stromal cells in turn ...
Podoplanin mediates stromal–immune crosstalk in the lymph node A preprint by Makris et al. shows that podoplanin is a key regulator of the functions of fibroblastic reticular cells in lymph nodes, by modulating interactions with immune cells. Erika E. McCartney Matthew B. Buechler Research Hig...
Herein, I review some of the physicochemical elements of stromal cells that are used to transport and guide immune cells and soluble molecules within LNs. 展开 关键词: stroma lymph node soluble material transport cellular migration DOI: 10.3389/fimmu.2012.00304 被引量: 15 ...
Adaptive immunity is initiated in lymphoid tissue where lymph node stromal cells (LNSCs) regulate immune responses through their intimate connection with leucocytes. We postulate that malfunctioning of LNSCs creates a microenvironment in which normal immune responses are not properly controlled, possibly ...
Lymph node (LN) stromal cells, particularly fibroblastic reticular cells (FRCs), provide critical structural support and regulate immunity, tolerance and the transport properties of LNs. For many tumors, metastasis to the LNs is predictive of poor prognosis. However, the stromal contribution to the...
stromal and resident dendritic cells provides a robust regulatory mechanism for the maintenance of intestinal tolerance. Similar content being viewed by others Postnatal expansion of mesenteric lymph node stromal cells towards reticular and CD34+stromal cell subsets...