Multipotent mesenchymal stromal cells (MSC) can be isolated and efficiently expanded from almost every single body tissue and have the ability of self-renewal and differentiation into various mesodermal cell lineages. Moreover, these cells are considered immunologically privileged, related to a lack of...
These cells are originated from both surrounding tissues and bone marrow. However, autophagy effects regarding these stromal cells are not exactly determined yet. Despite the importance of autophagy in crosstalk between cancer cells and stromal cells, it contributes to vascular compartment to finally ...
theRAB3GAP1gene identified through GWAS was independently replicated. Rare variants in theZNF469gene (mutated in corneal dystrophy Brittle Cornea Syndrome) and in theTGFBIgene (mutated in multiple corneal epithelial–stromal TGFBI dystrophies) have been repeatedly identified in familial and sporadic KC ...
Further, co-expression of an Sp7ZF/Sp1 chimeric protein-encoding construct with Dlx5 did not induce osteoblast marker genes in C3H10T1/2 cells, a stromal cell line with osteogenic potential (Katagiri et al., 1990), in contrast to WT Sp7 (Figure S5K). Together, these data suggest that ...
and reduced vision. The disease usually manifests itself during the late teens or early twenties and shows a slow progression for the next decade or two. The clinical signs of keratoconus are highly variable depending on the stage of progression of the disease and may include stromal thinning, ...
and reduced vision. The disease usually manifests itself during the late teens or early twenties and shows a slow progression for the next decade or two. The clinical signs of keratoconus are highly variable depending on the stage of progression of the disease and may include stromal thinning, ...
Malignant lymphomas comprise over 60 different neoplastic disorders that originate from lymphoid cells. The different lymphoma subtypes can be distinguished based on a combination of histological, immunophenotypic, genetic and clinical features. Malignant lymphomas are among the malignancies with the highest ...
39 However, this would not explain the redistribution of phosphorylated NCC toward more distal DCT segments and the increased pNCC levels that are found in Umod−/− mice at baseline. Our results suggesting that uromodulin facilitates NCC phosphorylation in stably transfected HEK cells support a...
Progenitors' superior therapeutic capacities are demonstrably effective against limb ischemia. Return the CD271, it's requested.Progenitor cells in insulin-resistant donors show reduced functionality and impairment.Adipose tissue stromal cells possess an exceptional angiogenic gene profile, a feature not ...
Multipotent mesenchymal stromal cells (MSC) can be isolated and efficiently expanded from almost every single body tissue and have the ability of self-renewal and differentiation into various mesodermal cell lineages. Moreover, these cells are considered immunologically privileged, related to a lack of...