In addition, we reported that one of the endothelial cell clusters withexpression exhibited strong chemotaxis and a weak angiogenic ability and expanded with disease progression. Furthermore, ligand-receptor-ba
Originally described as noncancerous cells within a tumor,stromal cellsare now typically defined asconnective tissue cellsof an organ. Stroma is comprised of theextracellular matrixand a number of cell types, including mesenchymal cells such as fibroblasts andpericytes, as well asendothelial cells.Str...
Endothelial cell modulation of bone marrow stromal cell osteogenic potential. FASEB J. 2005; 19 :665–667. [ PubMed ]Kaigler D, Krebsbach PH, West ER, Horger K, Huang YC, Mooney D. West ER et al. Endothelial cell modulation of bone marrow stromal cell osteogenic potential. The FASEB ...
magnetic-activated cell sorting; SSC, side scatter.b, UMAP plots of stroma-enriched cells from nine human MFLN samples and ten FL samples, coloured by cell type (top). Major NHC components from MFLN samples and FL samples are shown separately (bottom left and bottom...
The development of stem cell technology in combination with advances in biomaterials has opened new ways of producing engineered tissue substitutes. In this study, we investigated whether the therapeutic potential of an acellular porous scaffold made of type I collagen can be improved by the addition...
As regards differentiation of donor MSCs, we observed donor cell-derived endothelial cells within the sheets (but not in the host myocardium), while there was no finding suggesting myogenic differentiation. Recent research has shed light on the ability of MSCs to stimulate endogenous progenitor cells...
NK cell: Natural killer cells CAF: Cancer-associated fibroblasts EC: Endothelial cell MSC: Mesenchymal stem cell TLR: Toll-like receptor IFN: Interferon TNF: Tumour necrosis factor IL: Interleukin TRM: Tissue-resident macrophage PDPN: Podoplanin ...
[61]. Although CAFs are the most abundant cell type in the tumour stroma, some questions related to CAFs remain unanswered, such as whether they originate from endothelial cells or pericytes participating in the formation of new blood vessels. Tumours can be thought of as ‘wounds that never ...
Inflammatory bowel diseases (IBD), innate lymphoid cells (ILC), T helper cell (Th), interleukin (IL), transforming growth factor-beta (TGF-β), regulatory B cells (Bregs), regulatory T cells (Tregs), regulatory dendritic cells (rDCs), natural killer T (NKT) cells, tumor necrosis factor ...
Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence Development of the dorsal aorta is a key step in the establishment of the adult bloodforming system, since hematopoietic stem and progenitor cells (HSPCs) ... P Sahai-Hernandez,C Pouget...