Within the context of the gut microbiome-brain axis, we discuss how perturbations in the gut microbiota can alter the stress axis and behavior. In addition, human studies on the possible role of gut microbiota in depression and anxiety are examined. Finally, we present some of the challenges ...
In conclusion, a temporary disruption of the gut microbiota in early-life results in very specific and long-lasting changes in visceral sensitivity in male rats, a hallmark of stress-related functional disorders of the brain-gut axis such as irritable bowel disorder....
Psychobiotics are a type of probiotic that affect cognitive and behavioral functions of the host via the gut–brain axis. Proposed mechanisms of action of psychobiotics include the modulation via the hypothalamus–pituitary–adrenal axis (HPA) axis, direct immune effects, and various neural, ...
We will focus on the influence of stress on the microbiota and the mechanisms by which microbiota can affect the stress response and behavioral outcomes with an emphasis on visceral pain. 展开 关键词: Brain‐Gut axis Gut microbiota Stress Visceral Pain ...
Semen quality and fertility has declined over the last 50 years, corresponding to ever-increasing environmental stressors. However, the cellular mechanisms involved and their impact on sperm functions remain unknown. In a repeated sampling human cohort s
Human brain and intestinal microbes reportedly maintain a constant bidirectional connection through diverse neural,endocrine, immune, and metabolic pathways. Increasing evidence indicates that this communication system, referred to as microbiota-gut-brain axis, enables the gut microbes to influence several as...
Stress & the gut-brain axis: Regulation by the microbiome - ScienceDirect At the 2016 Neurobiology of Stress Workshop in Newport Beach, CA, a group of experts presented the symposium "The Microbiome: Development, Stress, and Disease". This report summarizes and builds upon some of the key ...
The brain-gut axis provides a bidirectional means of communication between the microbiota within the gut and the brain. Stress acting via the brain can result in alteration of the microbial composition of the gut, but increasing evidence... LV Scott,G Clarke,TG Dinan - 《Mod Trends Pharmacopsy...
Or if you’re feeling angry or upset and don’t feel like eating? These are all examples of this strong connection between your emotions and your digestive system. This connection is called the “gut microbiota-brain axis”or simply the “gut-brain axis”.Researchshows that when we’re str...
Gut-brain-axis Gut microbiota Adaptive immunity Regulatory T cells Th17 cells Neuroinflammation Polyphenols Metabolome Psychiatric disorders Aryl hydrocarbon receptor 1. Introduction Chronic stress and its corresponding physiological adaptations are major drivers of stochastic depression and anxiety. During times ...