Gut microbiota-brain axis is the two-way information communication network between intestinal microbiota and brain, whosecomposition includes gut microbes and their metabolite, intestinal tract, enteric nervous system and the sympathetic and parasym-pathetic branch of the autonomic nervous system, neural ...
该小肽通过靶向“菌肠脑轴”（microbiota-gut-brain axis），刺激肠道上皮细胞产生更多厌食激素（尿鸟苷素，UGN），并促进下丘脑中具有抑食效应的POMC神经元活动增强，降低动物摄食量；此外，该小肽还可以显著改善肠道菌群平衡，提高嗜黏蛋白阿克曼氏菌(Akkermansia muciniphila)丰度。首先，研究人员从人体体液防御素...
该研究利用小鼠、大鼠以及猕猴等多种饮食性肥胖动物模型,研究并证实了由该团队自主开发的可口服小肽D3具有显著的减重作用。该小肽通过靶向“菌肠脑轴”(microbiota-gut-brain axis),刺激肠道上皮细胞产生更多厌食激素(尿鸟苷素,UGN),并促进下丘脑中具有抑食效应的POMC神经元活动增强,降低动物摄食量;此外,该小肽...
该小肽通过靶向“菌肠脑轴”(microbiota-gut-brain axis),刺激肠道上皮细胞产生更多厌食激素(尿鸟苷素,UGN),并促进下丘脑中具有抑食效应的POMC神经元活动增强,降低动物摄食量;此外,该小肽还可以显著改善肠道菌群平衡,提高嗜黏蛋白阿克曼氏菌(Akkermansia muciniphila)丰度。 首先,研究人员从人体体液防御素被肠液酶...
Evidence has unveiled the bidirectional communication between the gut microbiome and the central nervous system, referred to as the “microbiota–gut–brain axis”. The microbiota–gut–brain axis represents an important regulator of glial functions, making it an actionable target to ameliorate the ...
gutmicrobiota-brainaxis肠道微生物-脑轴 系统标签: microbiotagutaxisbrain微生物肠道 ChineseMedicalJournal¦October5,2016¦Volume129¦Issue192373 ReviewArticle IntroductIon Thelatestresearchshowedthatchangesingutmicrobiota couldaffectthebrain’sphysiological,behavioral,and cognitivefunctions. [1‑5] In2013,the...
Gut-Brain axis 肠道菌群还可通过代谢产物、刺激免疫细胞分泌细胞因子、诱导肠内分泌细胞产生5-HT、影响神经细胞等方式调节大脑活动,最终影响人的行为、心情、学习和记忆等活动[1-2]。 1.Collins SM, Surette M, Bercik P: The interplay between the intestinal microbiota and the brain. Nat Rev Microbiol 2012...
In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal hosts to regulate the development and function of the immune, metabolic and nervous systems through dynamic bidirectional communication along the ‘gut–brain axis’. These processes may affect human health, as...
原名:Involvement of the microbiota-gut-brain axis inchronic restraint stress: disturbances of the kynurenine metabolic pathway inboth the gut and brain 译名:菌群-肠脑轴参与慢性束缚应激:肠和脑中犬尿氨酸代谢途径的紊乱 期刊:Gut Microbes IF:7.74 ...
nature publishing group Review Gut microbiota, the immune system, and diet influence the neonatal gut–brain axis Michael P. Sherman1, Habib Zaghouani1,2,3 and Victoria Niklas4 The conceptual framework for a gut–brain axis has existed for decades. The Human Microbiome Project is ...