Within the context of the gut microbiome-brain axis, we discuss how perturbations in the gut microbiota can alter the stress axis and behavior. In addition, human studies on the possible role of gut microbiota in depression and anxiety are examined. Finally, we present some of the challenges ...
By studying the function of two important stress-sensing transcriptions namely Nrf2/CncC and HSF1 in ISCs, we have uncovered an unprecedented role of these genes in stem cell identity and the regulation of the gut microbiome. These findings could shed light on the mechanisms altered during aging...
Gut Microbiome and StressThe roles of intestinal microorganisms in communication between the gut and brain are gaining increasing recognition. Microbiome driven gut-to-brain communication has been shown to influence stress-redoi:10.1007/978-3-319-23213-3_11Winnie-Pui-Pui Liew...
Early-life stress and the gut microbiome: A comprehensive population-based investigation We examined early life stress and stool microbiome in the general population.We found no significant association between overall ELS and children's microbi... RH Mulder,R Kraaij,IK Schuurmans,... - 《Brain Be...
The Gut Microbiome Regulates Psychological Stress-Induced Inflammation in Sickle Cell Diseasedoi:10.1182/blood-2019-122331Psychological stress (PS) is reported ... C Xu,S Lee,PS Frenette - 《Blood》 被引量: 0发表: 2019年 Postinfectious irritable bowel syndrome. Adverse psychological factors contribut...
Mental stress has long been linked to flare-ups of gastrointestinal conditions such as irritable bowel syndrome (IBS). Now, researchers have uncovered exact details of one way that stress can harm the intestines — by setting off a biochemical cascade that reshapes the gut microbiome....
Microbiome(2024) Therapeutics for neurodegenerative diseases by targeting the gut microbiome: from bench to bedside Yuan-Yuan Ma Xin Li Yan-Jiang Wang Translational Neurodegeneration(2024) Gut microbiota-host lipid crosstalk in Alzheimer’s disease: implications for disease progression and therapeutics ...
Marchesi, C. Hill, and R.D. Sleator. 2012. Mining the human gut microbiome for novel stress resistance genes. Gut Microbes 3:394-397.Culligan EP, Marchesi JR, Hill C, et al. Mining the human gut microbiome for novel stress resistance genes[J]. Gut Microbes, 2012, 3(4):394-397....
This is believed to be the first study to explore the intersection of resiliency, the brain, and the gut microbiome. “If we can identify what a healthy resilient brain and microbiome look like, then we can develop targeted interventions to those areas to reduce stress,” said Arpana Gupta,...
and chronic stress. Our results show that stress has an impact on CYP mRNA expression, but it is mainly chronic stress that has a significant effect on enzyme activities along with the gut microbiome. In acutely stressed mice, we observed significant changes at the mRNA level, however, the ...