Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.包装清单: 产品编号 产品名称 包装 L16581 STK11 Knockout Lentivirus 108 TU — 说明书 1份 保存条件:-80℃保存,至少一年有效。
2019, 22(4): 233-238. [Chen J, Jiang D, Huang F. Advances of the Correlation between Driver Gene Status and Immunotherapy in Non-small Cell Lung Cancer[J]. Zhongguo Fei Ai Za Zhi, 2019, 22(4): 233-238.]
This article reviews the research progress of the correlation between STK11 gene mutation and immunotherapy on NSCLC.夏思雨赵梓彤李里Cancer Research on Prevention & Treatment
[6] Borun P, De Rosa M, Nedoszytko B, Walkowiak J, Plawski A. Specific Alu elements involved in a significant percentage of copy number variations of the STK11 gene in patients with Peutz-Jeghers syndrome. Fam Cancer. 2015 Sep;14(3):455-61. doi: 10.1007/s10689-015-9800-5. PMID: ...
【 Key words 】STK11 gene; Cervical cancer; Gene expression 宫颈癌是继乳腺癌后最常见的妇科恶性肿瘤,死亡率位居妇女恶性肿瘤首位。高危型人乳头瘤病毒(human papilloma virus,HPV)是导致宫颈癌的关键致病因子,其发病原因与发生过程被多种因子综合影响。研究显示,基因启动子甲基化的研究,在恶性肿瘤生物学领域研究...
which could be an indicator for the diagnosis of PJS in this fa m ily.And it may lead to a higher risk of cancer in patients. Keywords:Peutz—Jeghcrs syndrome;STK1 1 gene;tr uncated mutation 黑斑息肉综合征(Peutz—Jeghers syndrome,PJs),又 称黑斑 胃肠道多发性息 肉病 ,是一种临床上少见...
Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] [中文简述(自动翻译):] 该基因,其编码的丝氨酸/苏氨酸激酶家族的一个成员,调节细胞极性和用作肿瘤抑制基因。在这种基因突变与黑斑息肉综合征,常染色体显性遗传...
Mutations in STK11gene in Czech Peutz-Jeghers patients. Vasovcák P,PuchmajerováA,Roubalík J,KrepelováA. BMC Medical Genetics . 2009Vasovcak P, Puchmajerova A, Roubalik J, Krepelova A. Mutations in STK11 gene in Czech Peutz-Jeghers patients. BMC Med Genet 2009; 10: 69...
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal ...
Objective To detect mutations of STK11 gene in peripheral blood and hamartomatous gastrointestinal polypi of 2 pedigrees and 3 sporadic patients with PJS. Methods Blood samples were obtained from some members in the 2 pedigrees, 3 sporadic patients, and 100 normal human controls, and tissue sample...