In study III, an important difference in mitochondrial shuttles was found between alpha and beta cells, highlighting the malate-aspartate shuttle to be critical for glucagon secretion. These findings were subsequently verified in mouse islets. In study IV, a striking difference in the activity of ...
Activation of the glucagon-like peptide 1 receptor augments insulin secretion by amplifying calcium signals by calcium induced calcium release (CICR). In the treatment of type 2 diabetes, use of the sulfonylureas that act on the ATP sensitive potassium channel, damages the beta cells, which ...
The chemistry of fear.(more)See all videos for this article When a threat is perceived, the sympathetic nerve fibres of the autonomic nervous system are activated. This leads to the release of certain hormones from the endocrine system. In physiological terms, a major action of these hormones ...
The release of hormones from the adrenal cortex is stimulated by: A. thyroid hormone. B. adrenocorticotropic hormone. C. oxytocin. D. antidiuretic hormone. E. luteinizing hormone.Give one example of humoral stimulus, neural stimulus, and hormonal stimulus for the release of hormon...
Glucagon secretion from pancreatic 伪-cells is regula... K Dan,RN Kulkarni - 《Islets》 被引量: 41发表: 2009年 Overexpression of Pre-Pro-Cholecystokinin Stimulates β-Cell Proliferation in Mouse and Human Islets with Retention of Islet Function We studied islet function by measuring glucose-...
What is the stimulus for the release of glucagon? Why are myelinated axons faster? What is the function of neurotransmitters in the brain? How do stimulants affect the peripheral nervous system? How fast do acinar cells produce enzymes? What mechanism releases neurotransmitter from...
The ability of the pancreatic -cells to adapt the rate of insulin release in accordance to changes in circulating glucose levels is essential for glucose homeostasis. Two spatial barriers imposed by the plasma membrane and inner mitochondrial membrane need to be overcome in order to achieve stringent...
We propose that the interaction of cAMP and Epac to trigger CICR explains, at least in part, the blood glucose-lowering properties of an insulinotropic hormone (glucagon-like peptide-1, also known as GLP-1) now under investigation for use in the treatment of type-2 diabetes mellitus....
Explain the mechanism of parathyroid hormone action, and the effects of its action. Explain the mechanism of release of neurotransmitters. Explain the sliding filament mechanism. Explain a physiological mechanism for a fever. Discuss a neurotransmitter or neuromodulator and describe its action...
NPR's Scott Horsley apparently couldn't find any conservatives for his report on Thursday's All Things Considered, as he played nothing but sound bites from President Obama and former economic advisor Jared Bernstein boost a possible mini-stimulus, including "help for public work...