Kadereit, By Suzanne
Over the last decades, the cancer survival rate has increased due to personalized therapies, the discovery of targeted therapeutics and novel biological agents, and the application of palliative treatments. Despite these advances, tumor resistance to che
BS1-1: Stem Cells, Cancer, and Cancer Stem Cells Significant advances in breast cancer prevention and treatment have come from strategies based on knowledge of mammary cell biology and the unique molecular fingerprints of individual tumors. GM Wahl - 《Cancer Research》 被引量: 0发表: 2011年 ...
Conventional wisdom on the potential of stem cells is about treatments that directly replace unhealthy tissues — but new research suggests certain stem cells can actually wage a war against cancer cells. A team led by Mohamed Abumaree at KAIMRC has demonstrated that mesenchymal stem cells (MSCs)...
Cancer stem cells (CSCs) It is postulated that cancer initiating cells, also named cancer progenitor cells or cancer stem cells (CSCs), are a population of cancer cells within a heterogeneous tumor that possess stem-cell-like characteristics, including self-renewal and differentiation, thus initiatin...
stem cells are rare immortal cells within a tumour that can both self-renew by dividing and give rise to many cell types that constitute the tumour, and can therefore form tumours. Such cells have been found in various types of human tumours and might be attractive targets for cancer ...
Dirks PB: Cancer: stem cells and brain tumors. Nature 2006, 444:687-688.Dirks PB.Cancer:stem cells and brain tumors. Nature . 2006Dirks PB. Cancer stem cells and brain tumors[J].Nature,2006,(7120):687-688.doi:10.1038/444687a.
CD133, a marker of tumour-initiating cells A variety of markers have been used to characterise the stem-like tumour-initiating cells. For example, in leukemias, TICs feature the CD44+/CD38− phenotype [5]. The prostate cancer TICs have been characterised by the CD44+/α2β1hi/CD133+ ph...
Stem Cells and Cancer Stem Cells, Volume 10 Therapeutic Applications in Disease and Injury Editors: M.A. Hayat Copyright: 2013 Available Renditions Hard cover Soft cover eBook Stem Cells and Cancer Stem Cells, Volume 11 Therapeutic Applications in Disease and injury Editors: M.A. Hayat...
cells endowed with unique self-renewal properties and tumorigenic potential is present in some, and perhaps all, tumors. Although our understanding of the biology of these putative cancer stem cells remains rudimentary, the existence of such cells has implications for current conceptualizations of ...