Because of the few effective treatments for many chronic kidney diseases, increasing consideration has been given to new regenerative therapies using stem cells. Recent advances in developmental biology and stem cell biology have led to the increased availability of renal stem/progenitor cells from ...
Kidney regenerationMesenchymal stem cellMetanephrosRenal progenitor cellCurrently many efforts are being made to apply regenerative medicine to kidney diseases using several types of stem/progenitor cells, such as mesenchymal stem cells, renal stem/progenitor cells, embryonic stem cells and induced ...
ESCs that are characterized by features of self-renewability and multilineage differentiation hold great promise in cell therapy and kidney regeneration. Numerous studies have shown that mouse embryonic stem cells (mESCs) can integrate into kidney compartments, suggesting a possible efficacy for kidney rep...
ESCs that are characterized by features of self-renewability and multilineage differentiation hold great promise in cell therapy and kidney regeneration. Numerous studies have shown that mouse embryonic stem cells (mESCs) can integrate into kidney compartments, suggesting a possible efficacy for kidney rep...
Understanding the mechanisms of repair and regeneration of the kidney after injury is of great interest because there are currently no therapies that promo... B Li,A Cohen,TE Hudson,... - 《Circulation》 被引量: 317发表: 2010年 Poor Cell Survival Limits the Beneficial Impact of Mesenchymal ...
The need for new methods to alleviate, cure, or prevent renal disease has fueled great interest in the topic of kidney stem cell biology. For over a decade now, the use of stem cells for regenerative medicine has been broadly heralded as the coming of a new age in healthcare [8]. Unfo...
Figure 4. Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) ameliorate renal inflammation. (a) Renal vein levels of monocyte-chemoattractant protein (MCP)-1, tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-1β, and IL-10. (b) Representative kidney IL-10 and IL-4 ...
Treatments with modified bone marrow stem cells may help kidney transplant patients ditch immunosuppressive drugs, reports a new study in a small group of people. The findings could reduce or eliminate the need for toxic immunosuppressive drugs -- up to 15-25 pills per day – that most transplan...
Transplanting autologous renal progenitor cells (RPCs), (kidney stem cells derived from self-donors), into rat models with kidney damage from pyelonephritis - a type of urinary infection that has reached the kidney - has been found to improve kidney stru
Eirin and Lerman [2] examine the use of mesenchymal stem cells in the treatment of chronic kidney disease. Qin, Long, Deng, and Zhang [3] describe the isolation, characterization, and potential use of urine-derived stem cells in the regeneration of bladder. As single cell therapy modalities ...