have found that injection with 5 × 107 iPSCs affected the smaller arteries of the kidneys with cellular emboli, leading to the reduction of blood reperfusion after ischemia. When carrying out cell therapy for treatment of AKI using iPSCs, the cell dose for transplantation and the ...
have found that injection with 5 × 107 iPSCs affected the smaller arteries of the kidneys with cellular emboli, leading to the reduction of blood reperfusion after ischemia. When carrying out cell therapy for treatment of AKI using iPSCs, the cell dose for transplantation and the ...
Recent advances in developmental biology and stem cell biology have led to the increased availability of renal stem/progenitor cells from multiple sources, including their isolation from embryonic and adult kidneys, and to the generation of kidney lineage cells by the directed differentiation of ...
Due to these properties, MSC transplantation has been used for the treatment of GVHD, and several autoimmune diseases, including autoimmune thyroditis [20], RA [17, 18] and MS [16] and implicated for allogeneic stem cell transplantation....
We suggest that resident SCs recently identified in the Bowman's capsule of adult human kidneys might prospectively be the ideal cell type for treatment of both acute and chronic renal injury because they display the potential to differentiate into multiple types of renal cells. However, BMSCs ...
Whentreating chronic kidney failure by using stem cells in Europe, lost function of the kidneys is restored, and immune system of the body is significantly strengthened. Injection of stem cells, on the one hand, restore the vessels of the kidney, and on the other – restore the renal tissue...
To validate and compare the cell distribution pattern in the lungs and the kidneys, ex vivo BLI was performed at 1 hour and day 8 after renal artery injection and at 1 hour after intravenous injection of the same number (2 × 105) of cells. The signal intensity from the lungs ...
The researchers divided 27 rats into three groups, two of which were modeled with an induced pyelonephritis in their right kidneys, while the third group did not have induced disease. RPCs were obtained from the diseased animals' left kidneys and injected into the right kidney six weeks later....
An important target for cell therapy is represented by tubular epithelial cells which after acute ischemic or toxic insults undergo dysfunction and detachment. Among adult stem cells, mesenchymal stromal/stem cells (MSC) are an attractive therapeutic tool by virtue of their unique biological properties...
Kidney transplantation is the best treatment for end-stage renal disease, but its implementation is limited by organ shortage and immune rejection. Side effects of current immunosuppressive drugs, such as nephrotoxicity, opportunistic infection, and tumo