with 5 × 107iPSCs affected the smaller arteries of the kidneys with cellular emboli, leading to the reduction of blood reperfusion after ischemia. When carrying out cell therapy for treatment of AKI using iPSCs, the cell dose for transplantation and the monitoring of renal blood perfusion ...
have found that injection with 5 × 107 iPSCs affected the smaller arteries of the kidneys with cellular emboli, leading to the reduction of blood reperfusion after ischemia. When carrying out cell therapy for treatment of AKI using iPSCs, the cell dose for transplantation and the ...
Stem cell therapyKidney disease arises from dysfunction of the kidneys due to a variety of factors, which impact the kidney but also kidney-related functions. There are, in fact, many forms of kidney or kidney-relateddoi:10.1007/978-3-319-55687-1_8Phuc Van Pham...
Kim JH, Park DJ, Yun JC, Jung MH, Yeo HD, Kim HJ, Kim DW, Yang JI, Lee GW, Jeong SH, Roh GS, Chang SH: Human adipose tissue-derived mesenchymal stem cells protect kidneys from cisplatin nephrotoxicity in rats. Am J Physiol Renal Physiol 2012;302:F1141-F1150. [PubMed] https:/...
We suggest that resident SCs recently identified in the Bowman's capsule of adult human kidneys might prospectively be the ideal cell type for treatment of both acute and chronic renal injury because they display the potential to differentiate into multiple types of renal cells. However, BMSCs ...
However, their use should be gradually tapered off to lower the risk of opportunistic infections and malignancies, as well as to prevent long-term toxicity to the central nervous, gastrointestinal and hematopoietic systems and kidneys. Therefore, there is a substantial need for novel immunosuppressive...
To validate and compare the cell distribution pattern in the lungs and the kidneys, ex vivo BLI was performed at 1 hour and day 8 after renal artery injection and at 1 hour after intravenous injection of the same number (2 × 105) of cells. The signal intensity from the lungs ...
kidneys is weak, which may be the reason for the poor homing effect of transplanted MSCs. The ultrasound-targeted disruption of microbubbles loaded with SDF-1 has the potential to increase the level of SDF-1 in targeted renal tissue, thereby promoting the homing of MSCs to early DN kidneys....
are hundreds of clinical trial investigating the use of stem cells to treat common and often life-threatening conditions such as heart disease, Alzheimer’s and diabetes. Within your child’s lifetime their cord blood may even be used to repair spinal damage, print kidneys or grow a new ...
Rather, the majority of intravenously injected cells are trapped by the lungs, liver, kidneys, and spleen [56, 57]. More proximal but still non-selective delivery via intracavitary or intra-aortic (with the distal aorta occluded) injection marginally improves cardiac uptake [56, 57], suggesting...