With the development of induced pluripo-tent stem cell technology, it is now possible to reprogram adult cells to differentiate into multiple cell types, including renal cells.1 Although induced pluripotent stem cells hold great promise for treatment of chronic diseases such as kidney failure in ...
Treatment ofchronic kidney failure by using stem cells in Europebased on the astonishing ability of stem cells to replace affected tissue cells, which leads to restoration of organ functionality. Injection of stem cells promote germination of new vascular pathways, bypassing the damaged ones, and als...
1.Costantini, F., and Kopan, R. (2010). Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development. Developmental cell 18, 698-712. 2.McMahon, A.P. (2016). Development of the ...
The prevalence of kidney diseases is emerging as a public health problem. Stem cells (SCs), currently considered as a promising tool for therapeutic application, have aroused considerable interest and expectations. With self-renewal capabilities and grea
A rising incidence of chronic kidney disease(CKD) has become a global social burden.Due to the lack of effective treatment,patients with end-stage chronic kidney disease have routinely received lifelong renal replacement therapy.Stem cell is recognized as a promising strategy of preventing the develop...
The pathogenesis of diabetic kidney dise... TP Griffin,WP Martin,N Islam,... - 《Current Diabetes Reports》 被引量: 18发表: 2016年 Stem cell therapy for ischaemic heart disease and congestive heart failure A promising approach to the treatment of chronic ischaemic heart disease (IHD) and ...
2024年4月30日,美国南加州大学凯克医学院博德干细胞研究所李中伟团队在Cell Stem Cell期刊发表了题为:Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease 的研究论文。
《Nature》《Stem Cell Report》《Kidney》科研三部曲 《Nature》真相：干细胞真的“死”了吗？《Stem Cell Report》《Kidney》科研“三部曲”- 快速认知干细胞 “衰老”“唤醒”与“修复”衰老是生物个体随时间推移的必然过程 表现为结构和机能衰退 适应性和抵抗力减退 人在30岁后 各项生理机能以每年0.75%~1%...
Acute liver failure (ALF) is a highly lethal disease, for which effective therapeutic methods are limited. Although allogeneic liver transplantation is a viable treatment method for ALF, there is a serious shortage of liver donors. Recent studies suggest that stem cell transplantation is a more pro...
Transplanting autologous renal progenitor cells (RPCs), (kidney stem cells derived from self-donors), into rat models with kidney damage from pyelonephritis - a type of urinary infection that has reached the kidney - has been found to improve kidney stru