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M. A critical role for Stat3 signaling in immune tolerance. Immunity, 19: 425- 436, 2003.CHENG F,WANG HW,CUENCA A,et al.A critical role for Stat3 signaling in immune tolerance[J].Immunity,2003,19(3):425-436.Cheng F, Wang HW, Cuenca A, Huang M, Ghansah T, et al. (2003) A ...
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[3] FALETTI L, EHL S, HEEG M. Germline STAT3 gain-of-function mutations in primary immunodeficiency: Impact on the cellular and clinical phenotype[J]. Biomed J, 2021,44(4):412-421. [4] HILLMER E J, ZHANG H, LI H S, et al. STAT3 signaling in immunity[J]. Cytokine Growth Factor...
We found that NHE-06 effectively suppressed NF-kappa B/IL-6/STAT3 signaling and enhanced antitumor immunity both in vitro and in HCC-bearing mice. In ... X Lu,G Wo,B Li,... - Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie 被引量: 0发表: 2018年 The anti-inflammatory ...
Importantly, restoration of IFN signaling through re-expression of endogenous STING, enforced expression of IFN response factor 7 or administration of recombinant type I IFN re-established antitumor immunity, inhibiting metastatic SCLC in vivo. These data show the potential of augmenting the innate ...
Further highlighting the regulatory role of Stat3 signaling in immune responses, Welte et al. have demonstrated that tissue-specific disruption of this signaling pathway during hematopoiesis is associated with an overactivated innate immunity leading to severe inflammatory bowel disease and lethality in ...
(2022) A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic cryptsImmunity[11] (2020) TH17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional iden...
2005. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nat. Med. 11: 1314-1321.Kortylewski M, Kujawski M, Wang T, Wei S, Zhang S, Pilon-Thomas S, et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor ...
A critical role for Stat3 signaling in immune tolerance [J]. Immunity, 2003, 19(3): 425-436. [4] Nefedova Y, Huang M, Kusmartsev S, et al. Hyper activation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer [J]. J Immunol, 2004, 172 (l): 464-474....