STAT3胃腺癌肿瘤麻醉抵抗作用细胞系统基因表达脉管内皮生长因子AIM: To investigate the difference in activation of STAT3signaling between two human stomach adenocarcinoma cell lines: 5-fluorouracil resistant cell line and its parental cell line, and to evaluate its relationship with the expression of ...
protein genes. Activated by IL31 through IL31RA. Acts as a regulator of inflammatory response by regulating differentiation of naive CD4+ T-cells into T-helper Th17 or regulatory T-cells (Treg): deacetylation and oxidation of lysine residues by LOXL3, leads to disrupt STAT3 dimerization and ...
Lewis, STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer, Stem Cells 32 (2014) 2571e2582.Wei W, Tweardy DJ, Zhang M, et al. STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of hu- ...
STAT3, also known as signal transducer and activator of transcription 3 isoform 1, is a member of the STAT protein family. It is a transcription factor activated in response to cytokine, growth factor, or hormone receptor signaling. Once this protein is
提供的STAT3人源重组蛋白(P01)产品为带有GST标签的人源STAT3全长序列重组蛋白,其对应的GeneID号为6774。 产品描述 与其它公司提供的重组蛋白不同,该STAT3人源全长重组蛋白(P01)产品为采用CFS的无细胞麦胚蛋白合成系统表达出来的重组蛋白,可表达出对细胞有毒性、易被蛋白酶降解的蛋白;并获得具有良好的可溶性,并有翻...
the upregulated PI3K-mTOR signaling in cancer cells can facilitate HIF-α activity and induce the angiogenic factors expression.36Furthermore, signal transducer and activator of transcription 3 (STAT3) was phosphorylated by mTORC1 in a hypoxic environment, thereby inducing HIF-1α RNA expression.37A...
中文名称:STAT3, HUMAN, 重组蛋白 (HIS) 中文同义词:STAT3, HUMAN, 重组蛋白 (HIS) 英文名称:STAT3 Protein, Human, Recombinant (His) 英文同义词:STAT3 Protein, Human, Recombinant (His) CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: ...
565 Mechanistically, it has been demonstrated that HCV-associated exosomes deliver RUNXOR and RUNX1 to MDSCs and promote the function of differentiation and suppressive functions of MDSCs through regulation of STAT3 signaling pathway. These results indicate that RUNXOR and RUNX1 may become a ...
Acute-phase response factor; APRFMGC16063; DNA-binding protein APRF; FLJ20882; HIES; signal transducer and activator of transcription 3 (acute-phase responsefactor); signal transducer and activator of transcription 3; STAT3 Product Datasheets ...
Research studies suggest the protein may also play important role in activating the NF-kappa-B signaling cascade. Defects in the EGGF gene are the cause of hypomagnesemia type 4 and dysregulation has been associated with the growth and progression of certain cancers. 仅用于科研。不用于诊断过程。