protein genes. Activated by IL31 through IL31RA. Acts as a regulator of inflammatory response by regulating differentiation of naive CD4+ T-cells into T-helper Th17 or regulatory T-cells (Treg): deacetylation and oxidation of lysine residues by LOXL3, leads to disrupt STAT3 dimerization and ...
与其它公司提供的重组蛋白不同,该STAT3人源全长重组蛋白(P01)产品为采用CFS的无细胞麦胚蛋白合成系统表达出来的重组蛋白,可表达出对细胞有毒性、易被蛋白酶降解的蛋白;并获得具有良好的可溶性,并有翻译后修饰、从而部分具有功能的蛋白。同时独有的全自动蛋白纯化技术则简便高效,将蛋白纯化过程中对蛋白的损伤降低到最...
中文名称:STAT3, HUMAN, 重组蛋白 (HIS) 中文同义词:STAT3, HUMAN, 重组蛋白 (HIS) 英文名称:STAT3 Protein, Human, Recombinant (His) 英文同义词:STAT3 Protein, Human, Recombinant (His) CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: ...
Human EGF Protein (PHG0313) in Functional Immunofluorescence analysis of signal transducer and activator of transcription 3 (STAT3) was performed using A549 cells treated with 100 ng/mL human EGF recombinant protein (Product # PHG0311) for 30 minutes. The cells were labeled with phospho-STAT3 (Se...
In addition, we demonstrated that FSK inhibits ΔNp63α activity through proteasomal degradation because the ΔNp63α protein level in the FSK-treated JEG3 cells was restored by MG132 (Fig.2e). However, in vivo ubiquitination assay performed in JEG3 cells expressing HA-tagged ubiquitin showed ...
Iwasaki K, Hailemariam K, Tsuji Y (2007) Protein inhibitor of activated STAT3 (PIAS3) interacts with activating transcription factor 1 (ATF1) and regulates the human ferritin H gene through an antioxidant responsive element. J Biol Chem 282: 22335-22343....
Furthermore, high levels of BCL3 protein were confirmed by immunoblotting in CC cells as compared with normal cervical epithelial cells. The positive expression of BCL3 was correlated with adverse prognostic features and reduced survival rate. In addition, BCL3 regulated STAT3 abundance in CC cells...
. These hEP-structures and natural blastocyst enriched genes were subjected to a simple gene set enrichment analysis using Reactome gene sets broadly related to signalling activities. This revealed an enrichment of several terms, including those related to PDGF, Interleukin, VEGF, PI3K, STAT3, and ...
Disruption of STAT3 can promote the apoptosis in human cancer cells. The close cooperation between TF regulations and chromatin modifications gives rise to an interesting question—how regulatory network collaborate with multiple chromatin states for controlling gene expression. To address this question, ...
Effects on ILC3s parallel Th17 differentiation, during which RORγT upregulates IL23R; IL-23 signaling and the phosphorylation and activation of STAT3 is subsequently essential for the differentiation and function of Th17 cells, as evidenced by defects in Th17 differentiation and immunity in patients...