STARR-seq enterpriseNature Structural & Molecular Biology 20, 308 (2013). doi:10.1038/nsmb.2539Author: Beth MoorefieldNature Structural &
Volume 20, page 308, (2013) Cite this article Download PDF From View current issue Submit your manuscript Beth Moorefield 1768 Accesses Explore all metrics Transcriptional enhancers are key determinants of cellular differentiation and development, but the fact that they function in a position-...
39,40] and later also in mammalian cells [41,42]. Targeted STARR-seq approaches use enrichment strategies (e.g., genomic fragments precipitated in ChIP-seq) to construct comprehensive libraries of candidate enhancer loci. This technique has been employed to examine enhancer...
The original protocol for STARR-seq has been successfully used to map cell type–specific (Arnold et al., 2013; Yáñez-Cuna et al., 2014) or inducible enhancers (Franz, Shlyueva, Brunner, Stark, & Basler, 2017; Shlyueva, Stelzer, et al., 2014) in Drosophila melanogaster cell lines...
regulatory region sequencing (STARR-seq) is a massively parallel reporter assay to identify transcriptional enhancers directly based on their activity in entire genomes for millions of candidates from arbitrary sources of DNA and to assess their activity quantitatively (Arnold et al., Science 2013). ...
regulatory region sequencing (STARR-seq) is a massively parallel reporter assay to identify transcriptional enhancers directly based on their activity in entire genomes for millions of candidates from arbitrary sources of DNA and to assess their activity quantitatively (Arnold et al., Science 2013). ...
Activity Maps Identified by STARR-seqArnold, Cosmas DRath, MartinaStark, Alexander