抗SSA/SSB阳性患者外周血CD4+Th和NK细胞水平较低,部分细胞因子水平较高,包括TNF-α和IL-17a,而这些改变对妊娠结局可能有影响。既往研究结果显示:抗SSA及/或抗SSB抗体阳性组的患者体外受精结局较差、习惯性流产的风险增加,抗SSA及/或抗SSB抗体阳性组患者的临床妊娠率、...
SSA and SSB antibodies are important in the formation of circulating immune complexes in SLEsurgery for rheumatoid arthritiseptic arthritisvasculitisfractures in AS patientscervical myelopathyMedical emergencies due to rheumatoid arthritis (RA) and ankylosing spondylitis (AS) can occur as a result of ...
METHODS:Twelve consecutive pregnant patients positive to anti-SSA/Ro ± anti-SSB/La antibodies in whom CHB was detected were prospectively evaluated from 2009 to 2014. The treatment protocol consisted of: weekly plasmapheresis, fortnightly intravenous immunoglobulins (IVIG), and daily 4 mg betamethasone...
应考虑4个主要因素:疾病活动/狼疮性肾炎、药物安全性、aPL,抗SSA/Ro和/或 抗SSB/La抗体。 附原文: ABSTRACT:Introduction: Systemic Lupus Erythematosus (SLE) mostly affects women during their childbearing years. Fertility is prese...
抗Ro/干燥综合征抗原A(Sjögren's syndrome type A,SSA)抗体和抗La/干燥综合征抗原B(Sjögren's syndrome type B,SSB)抗体都属于抗核抗体谱,常见于系统性红斑狼疮、干燥综合征、未分化结缔组织病及无症状患者,约1%的孕妇抗SSA...
Analysis of adverse neonatal outcomes in pregnant women with positive anti-Ro/SSA and anti-La/SSB antibodies 引用 收藏 分享 摘要 目的探讨孕妇抗Ro/干燥综合征抗原A(SSA)抗体和(或)抗La/干燥综合征抗原B(SSB)抗体阳性与新生儿不良结局的关系。方法本研究为回顾性研究,选取2017年1月至2022年6月于北京大学...
Anti-Ro(SSA) and La(SSB) antibody determinations have become important serologic tests in the evaluation of lupus erythematosus and Sjgren's syndrome patients. These antibodies appear to identify a group of lupus patients with prominent skin diseases. Although much of the initial investigations regard...
In addition, NMOSD patients with anti-SSA/Ro antibody showed the presence of more frequent anti-ANA antibodies (p = 0.002), anti-SSB/La antibody (p < 0.001), anti-dsDNA antibody (p < 0.002), Sjogren's syndrome (SS, p < 0.001) and systemic lupus erythematosus (SLE, p = 0.045). ...
抗Ro/SSA和La/SSB自身抗原的自身抗体最早是在干燥综合征和系统性红斑狼疮(systemic lupus erythematosus, SLE)患者中发现。随后的研究表明,其他自身免疫性疾病患者体内可能也有抗Ro/SSA抗体,包括系统性硬化症、特发性炎性肌病(idiopathic inflammatory myopathy, IIM)、间质性肺疾病(interstitial lung disease, ILD)、混...
Congenital heart block (CHB) is known to associate with the presence of anti-Ro/SSA and anti-La/SSB antibodies in the mother and is characterized by ... A Ambrosi,M Wahren-Herlenius - 《Arthritis Research & Therapy》 被引量: 67发表: 2012年 Anti-Ro (SSA) and anti-La (SSB) antibodies...