SSA and SSB antibodies are important in the formation of circulating immune complexes in SLEsurgery for rheumatoid arthritiseptic arthritisvasculitisfractures in AS patientscervical myelopathyMedical emergencies due to rheumatoid arthritis (RA) and ankylosing spondylitis (AS) can occur as a result of ...
抗SSA抗体和抗SSB抗体是原发性干燥综合征的标志抗体,存在于40%-80%的患者。具有抗SSA/SSB抗体的患者全身、血液学和免疫改变的患病率较高。在免疫学研究中,抗核抗体(ANA)最常见,而抗SSA抗体是特异的。此外,抗SSA抗体和抗SSB抗体可能在SS临床...
抗SSA/SSB阳性患者外周血CD4+Th和NK细胞水平较低,部分细胞因子水平较高,包括TNF-α和IL-17a,而这些改变对妊娠结局可能有影响。 既往研究结果显示:抗SSA及/或抗SSB抗体阳性组的患者体外受精结局较差、习惯性流产的风险增加,抗SSA及/或抗SSB抗体阳性组患者的临床妊娠率、...
andRFforpSSwere77.1%,62.9%,25.7%,80%,and51.4%respectively.ThespecificityofthethreespeciesantibodywithRFbyjointdetectionwassignificantlyhigherthansingleantibody,thespecificitywas91.4%.Whenanti-SSAandanti-SSBantibodieswereallnegative,thespecificityofanti-α-fodrinandRFwas75%.Conclusions Thejointdetectionofanti-...
联合检测抗SSA、抗SSB具有相对较好的特异性为57%。结论ANA阳性患者,联合抗SSA、抗SSB判断有助于提高原发性干燥综合征诊断的特异性 关键字:抗核抗体;干燥综合征;抗SSA;抗SSB [中图分类号] [文献标识码] B [文章编号] 1673-9701(2016)13-0125-04 Combination of ANA,anti-SSA and anti-SSB detection in ...
结论:用免疫印迹法和免疫扩散检测SSA/SSB血清类型与疾病诊断范围相关。 附原文:Objective:To determine the diagnostic distribution in a consecutive anti-SSA and/oranti-SSB positivepopulation.Methods: A total of 15 937 serum samples from 10550 consecutive patients were analysed for antinuclearantibodies (ANAs...
METHODS:Twelve consecutive pregnant patients positive to anti-SSA/Ro ± anti-SSB/La antibodies in whom CHB was detected were prospectively evaluated from 2009 to 2014. The treatment protocol consisted of: weekly plasmapheresis, fortnightly intravenous immunoglobulins (IVIG), and daily 4 mg betamethasone...
抗SSA抗体是1962年在干燥综合征患者体内发现的第一个抗体,随后在1969年,两个不同研究团队分别在名为“Ro”的SLE患者体内和另一名SS患者体内发现抗SSA抗体,因此抗SSA抗体又名抗Ro抗体。1974年抗La抗体被检测报道,后经交换抗原和血清证实抗Ro抗体就是抗SSA抗体,而抗La抗体就是抗SSB抗体[1]。
Anti-Ro(SSA) and La(SSB) antibody determinations have become important serologic tests in the evaluation of lupus erythematosus and Sjgren's syndrome patie... TT Provost - 《Keio J Med》 被引量: 21发表: 1991年 Anti-Ro/SSA and La/SSB antibodies [review] Ro/SSAla/SSBanti-ENAsystemic lup...
Abstract:Antibodies to Ro and/or La antigens (Ro/La) were detected in patients with con-nective tissue diseases (CTD),non-CTD and normal control by counterimmunoelectrop-horesis (CIE). 引用本文 张建中, 马圣清, 秦俭, 王光超. 抗Ro(SSA)、抗La(SSB、Ha)抗体检测及其临床意义[J]. 中华皮肤...