Kit signaling through PI 3- kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation. EMBO J. 17, 6250-6262 (1998)Timokhina I, Kissel H, Stella G, Besmer P: Kit signalling through PI3-kinase and Src kinase pathways: an essential role for...
Src kinase pathway is a potential candidate for molecular targeted therapy of non-small cell lung cancers (NSCLC) that show exon 19 deletion mutation or ot... Src kinase pathway is a potential candidate for molecular targeted therapy of non-small cell lung cancers (NSCLC) that show exon 19 ...
Src Inhibitors on signaling pathway are available at Adooq Bioscience. Check Src pathway , inhibitors reviews and assay information.
Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications. Tepper CG et al (2006) Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implicatio... ...
452 P-cadherin Activates Src-kinase – a New Signaling Pathway With Implications in Breast Cancer Progression - European Journal of Cancerdoi:10.1016/S0959-8049(12)71125-5A.S. RibeiroA. VieiraB. SousaA. AlbergariaR. SerucaF.C. Schmitt...
Heidinger, V. et al. Metabotropic glutamate receptor 1-induced upregulation of NMDA receptor current: mediation through the Pyk2/Src-family kinase pathway in cortical neurons.J. Neurosci.22, 5452–5461 (2002). CASPubMedPubMed CentralGoogle Scholar ...
2007 Bentham SciencePublishers Ltd., Synthetic Src-Kinase Domain Inhibitors andTheir Structural RequirementsSilvia Schenonei,*, Fabrizio Manetti 2 and Maurizio Botta 2【2】Synthetic Src-Kinase Domain Inhibitors Anti-Cancer Agents in Medicinal Chemi 22、stry, 2007, Vol. 7, No. 6 663【3】The Src ...
This study investigated the role of the kinase pathway in myofibroblast activation in vitro and fibrogenesis in vivo. The profibrotic cytokine, transforming β1 (TGF-β1), induced rapid activation of kinase, which led to of lung fibroblasts. The kinase inhibitor AZD0530 (saracatinib) blocked TGF...
Src 及其信号通路在肿瘤发生过程中的作用
摘㊀要:类固醇受体辅激活因子(ＳｔｅｒｏｉｄｒｅｃｅｐｔｏｒｃｏａｃｔｉｖａｔｏｒꎬＳｒｃ)是一种由Ｓｒｃ原癌基因编码的非受体型酪氨酸激酶ꎬ属于Ｓｒｃ家族蛋白激酶(Ｓｒｃ￣ｆａｍｉｌｙｋｉｎａｓｅｓꎬＳＦＫｓ)的核心成员.Ｓｒｃ广泛存在于人体细胞中ꎬ可调节细胞分裂㊁运动㊁黏附㊁血管生成和存活...