SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with...
(-20℃) 相关类别: 抗原 概述 Fusion protein corresponding to a region derived from 270-523 amino acids of human SRC 技术规格 Full name: Synonyms: Swissprot: Gene Accession: Purity: Expression system: Tags: Background: SRC proto-oncogene, non-receptor tyrosine kinase ASV; SRC1; c-SRC; p60-...
Full Name SRC proto-oncogene, non-receptor tyrosine kinase Research Areas Cancer>>Signal Transduction>>Signaling Pathway>>Representative pathway>>Apoptosis Signaling pathway>>Apoptosis Intracellular Kinases Immunology>>Inflammation / Inflammatory Mediator>>Pattern Recognition Receptors>>C-type Lectin Receptors ...
It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating ...
Pyruvate kinase (PK), contrary to what its name suggests, catalyses the conversion of phosphoenolpyruvate (PEP) into pyruvate. As with other glycolytic enzymes, the PK isoenzyme PKM2 (the ‘muscle’ isoform, also expressed in many other cell types) was promptly identified as a Src substrate in...
Download: Download full-size image Fig. 1. Major transport systems implicated in the generation and modulation of the Ca2 + transient. The drawing depicts the activation of a Src-family kinase (SFK) by a G protein-coupled receptor (GPCR) with associated trimeric G protein (α, β, γ) whi...
Loss of function of the transmembrane protein, CSK-binding protein (CBP)/phosphoprotein associated with GEMs (PAG) in colon cancer cells prevents the recruitment of the tyrosine kinase CSK, and therefore the phosphorylation of Tyr530 of SFK, which bring them back in a close inactive conformation....
Protein full name Neuronal proto-oncogene tyrosine-protein kinase Src Synonyms SRC, ASV, SRC1, c-p60-Src, SRC proto-oncogene, non receptor tyrosine kinase, THC6 Immunogen Recombinant protein corresponding to Mouse Src Isotype IgG Purity Affinity purification ...
The Pro-atherogenic Cytokine Interleukin-18 Induces CXCL16 Expression in Rat Aortic Smooth Muscle Cells via MyD88, Interleukin-1 Receptor-associated Kinase, Tumor Necrosis Factor Receptor-associated Factor 6, c-Src, Phosphatidylinositol 3-Kinase, Akt, c-Jun N-terminal Kinase, and Activator Protein-...
proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme...