Scheele JS, Kolanczyk M, Gantert M, et al. The Spt-Ada-Gcn5-acetyltransferase complex interaction motif of E2a is essential for a subset of transcriptional and oncogenic properties of E2a-Pbx1. Leuk Lymphoma. 2009;50(5):816-828.
V. (2015). Spt-Ada-Gcn5-acetyltransferase (SAGA) complex in plants: genome wide identification, evolutionary conservation and functional determination. PLoS One 10:e0134709. doi: 10.1371/journal.pone.0134709.Srivastava R, Rai KM, Pandey B, Singh SP, Sawant SV (2015) Spt-Ada-Gcn5-...
Gene regulationCytoskeletonCancerNeurodegenerationThe Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex is a critical regulator of gene expression and is highly conserved across species. Subunits of SAGA are arranged in discrete modules with lysine aceyltransferase and deubiquitinase activities...
SAGA(Spt-Ada-Gcn5 acetyltransferase)复合物是真核生物中高度保守的蛋白复合体,参与转录激活,mRNA转运等诸多生物学过程.为了探究SAGA复合物亚 基的潜在生物学功能,文章以裂殖酵母(Schizosaccharomyces pombe)SAGA复合物核心结构亚基Spt20为诱饵蛋白进行酵母双杂交筛选,获得了Ppb1蛋白.Ppb1 是真核生物重要信号分子-钙调...
spt abbreviation for (Navigation) seaport Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014 spt. seaport. Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries ...
GCN5 (KAT2A) is a member of the GNAT (Gcn5-related N-acetyltransferase) family of HATs. In metazoans this enzyme is found in two functionally distinct coactivator complexes, SAGA (Spt Ada Gcn5 acetyltransferase) and ATAC (Ada Two A-containing). These two multiprotein complexes comprise ...
Histone H2B deubiquitination is performed by numerous deubiquitinases in eukaryotic cells including Ubp8, the catalytic subunit of the tetrameric deubiquitination module (DUBm: Ubp8; Sus1; Sgf11; Sgf73) of the Spt-Ada-Gcn5 acetyltransferase (SAGA). Ubp8 is linked to the rest of SAGA through...
Spt-Ada-Gcn5-Acetyltransferase spt. Spta SPTB SPTB Sptc SPTCA SPTCEN SPTCL SPTCo SPTD SPTE SPTF SPTG SPTGA SPTGP Spth SPTI SPTIG SPTIMRM SPTJ SPTK SPTL SPTLC SpTLT SPTM SPTMG SPTMS SPTN SPTO SPTP SPTPA ▼Complete English Grammar Rules is now available in paperback and eBook forma...
Background Histone H2B deubiquitination is performed by numerous deubiquitinases in eukaryotic cells including Ubp8, the catalytic subunit of the tetrameric deubiquitination module (DUBm: Ubp8; Sus11; Sgf11; Sgf73) of the Spt-Ada- Gcn5 acetyltransferase (SAGA). Ubp8 is linked to the rest of...
Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. The transcriptional adaptor protein Gcn5 has been identified as a nuclear histone acetyltransferase (HAT). Although recombinant yeast Gcn5 efficiently...