Stem cell-based cell therapy for spinal cord injury. Kim BG,Hwang DH,Lee SI,et al. Cell Transplantation . 2007Kim BG, Hwang DH, Lee SI, Kim EJ, Kim SU. Stem cell-based cell therapy for spinal cord injury. Cell Transplant. 2007;16(4): 355-364....
In his Correspondence 'Caution urged in trial of stem cells to treat spinal-cord injury' (Nature 458,29; 2009), Yves Barde questions the wisdom of testing oligodendrocyte precursors derived from embryonic stem (ES) cells in patients, despite the promise that such cells hold for repairing these...
Spinal cord injury is one of the main causes of disability in the young population. Based on the underlying pathological changes, many modalities of treatments have been trialed. However, the most promising so far, has been the replacement of lost cellular elements, using stem cells and non-ste...
重点推荐 脊髓损伤模型(Spinal Cord Injury, SCI)是用于研究脊髓损伤的病理生理机制以及探索治疗方法的重要工具。 (A)从T2棘突开始,向头部方向制作一个1.5-2厘米的纵向皮肤切口,暴露皮下脂肪层。 (B)切除一小部分脂肪,以便于触摸到T2棘突。 (C)以T2棘突作为解剖标志,向头部方向切开肌肉层。通过钝性分离,分离肌...
Mesenchymal stem cellsAbstract A spinal cord injury (SCI) is any injury of the spinal cord caused due to trauma and mostly comprise of damage to the nerves associated with the spinal cord and they can be classified as being complete or incomplete. Spinal cord injuries account for a majority ...
Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues, which results in motor and sensory dysfunction, dystonia, and pathological reflex that ultimately lead to paraplegia or tetraplegia. A loss of cells, axon regeneration failure, and time-sensitive ...
Stem cell therapy has the potential to provide a valuable treatment approach for spinal cord injury, but no consensus yet exists regarding which type of stem cell is likely to be most effective in the clinical setting. In this article, Sahni and Kessler
In his Correspondence 'Caution urged in trial of stem cells to treat spinal-cord injury' (Nature 458, 29; 2009), Yves Barde questions the wisdom of testing oligodendrocyte precursors derived from embryonic stem (ES) cells in patients, despite the promise that such cells hold for repairing these...
Patients treated with these stem cells experienced increased sensation from pinpricks and light touches, increased muscle strength and better sphincter control, results show. "In spinal cord injury, even a mild improvement can make a significant difference in that patient's qualit...
Spinal cord injury (SCI) is the damage to the spinal cord that can lead to temporary or permanent loss of function due to injury to the nerve. The SCI patients are often associated with poor quality of life. This review discusses the current status of me